Entrez Summary: This gene is intronless and encodes a member of the ubiquitin-conjugating enzyme family. The protein product is 91% identical to ubiquitin-conjugating enzyme E2N, a multi-exon gene product. This locus represents a polymorphic pseudogene, where some individuals contain an allele that can encode a full-length protein, while others have a non-functional allele containing a premature stop codon (reference SNP rs237520) that truncates the coding sequence. [provided by RefSeq, Jun 2014].
UniProt Summary: N/A
Pfam DomainsGO Terms
Pfam Domains
UQ con
GO Terms
protein K63-linked ubiquitination
ubiquitin conjugating enzyme activity
postreplication repair
protein polyubiquitination
DNA repair
protein ubiquitination
DNA metabolic process
protein modification by small protein conjugation
cellular response to DNA damage stimulus
protein modification by small protein conjugation or removal
cellular response to stress
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)