USH2A

• Official Symbol: USH2A
• Official Name: usherin
• Aliases and Previous Symbols: N/A
• Entrez ID: 7399
• UniProt: O75445
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene encodes a protein that contains laminin EGF motifs, a pentaxin domain, and many fibronectin type III motifs. The protein is found in the basement membrane, and may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIa and retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].
• UniProt Summary: Involved in hearing and vision.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 4139
• Expression level (log2 read counts): -1.24

Expression Distribution

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USH2A Expression in NALM6 Cells: -1.24