UniProt Summary: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. {ECO:0000269|PubMed:14550283}.
Pfam DomainsGO Terms
Pfam Domains
7tm 1
GO Terms
urotensin II receptor activity
G protein-coupled peptide receptor activity
neuropeptide signaling pathway
regulation of blood vessel diameter
regulation of tube diameter
regulation of tube size
vascular process in circulatory system
regulation of blood pressure
blood circulation
circulatory system process
regulation of anatomical structure size
G protein-coupled receptor activity
G protein-coupled receptor signaling pathway
integral component of plasma membrane
system process
membrane
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739