Entrez Summary: The protein encoded by this gene is a striated muscle protein and belongs to the Xin actin-binding repeat-containing protein (XIRP) family. The protein functions to protect actin filaments during depolymerization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017].
UniProt Summary: N/A
Pfam DomainsGO Terms
Pfam Domains
Xin
GO Terms
stress fiber
negative regulation of protein binding
negative regulation of binding
actin filament binding
regulation of protein binding
actin filament organization
regulation of binding
focal adhesion
supramolecular fiber organization
actin cytoskeleton organization
actin filament-based process
cytoskeleton organization
negative regulation of molecular function
RNA binding
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739