ZMYND15
Gene Information
- Official Symbol: ZMYND15
- Official Name: zinc finger MYND-type containing 15
- Aliases and Previous Symbols: N/A
- Entrez ID: 84225
- UniProt: Q9H091
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a MYND-containing zinc-binding protein with a nuclear localization sequence. A similar gene in mice has been shown to act as a testis-specific transcriptional repressor by recruiting histone deacetylase enzymes to regulate spatiotemporal expression of many haploid genes. This protein may play an important role in spermatogenesis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012].
- UniProt Summary: Acts as a transcriptional repressor through interaction with histone deacetylases (HDACs). May be important for spermiogenesis. {ECO:0000250|UniProtKB:Q8C0R7, ECO:0000303|PubMed:24431330}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 8967
- Expression level (log2 read counts): -4.79
ZMYND15 Expression in NALM6 Cells: -4.79
