UniProt Summary: Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity (PubMed:24521053). May bind to specific miRNA hairpins (PubMed:28431233). {ECO:0000269|PubMed:24521053, ECO:0000269|PubMed:28431233}.
Pfam DomainsGO Terms
Pfam Domains
zf-met
GO Terms
miRNA binding
double-stranded RNA binding
enzyme binding
positive regulation of apoptotic process
positive regulation of programmed cell death
positive regulation of cell death
zinc ion binding
nucleolus
RNA binding
regulation of apoptotic process
regulation of programmed cell death
regulation of cell death
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)