ACAP3

Entrez Summary: N/A
UniProt Summary: GTPase-activating protein for the ADP ribosylation factor family. {ECO:0000305}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

neuron migration
growth cone
GTPase activator activity
positive regulation of GTPase activity
regulation of GTPase activity
regulation of neuron projection development
regulation of neuron differentiation
regulation of plasma membrane bounded cell projection organization
regulation of cell projection organization
positive regulation of hydrolase activity
regulation of neurogenesis
regulation of nervous system development
regulation of cell development
cell migration
cell motility
localization of cell
regulation of hydrolase activity
locomotion
positive regulation of catalytic activity
generation of neurons
movement of cell or subcellular component
neurogenesis
positive regulation of molecular function
regulation of cell differentiation