AOC1

Entrez Summary: N/A
UniProt Summary: Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

diamine oxidase activity
cellular response to copper ion starvation
propane-1,3-diamine oxidase activity
response to azide
methylputrescine oxidase activity
histamine oxidase activity
cellular response to azide
response to copper ion starvation
cellular response to heparin
response to heparin
primary amine oxidase activity
response to anticoagulant
cellular response to histamine
quinone binding
response to histamine
cellular response to copper ion
response to copper ion
copper ion binding
drug binding
specific granule lumen
amine metabolic process
peroxisome
bicellular tight junction
cellular response to ammonium ion
xenobiotic metabolic process
cellular response to starvation
heparin binding
response to ammonium ion
cellular response to xenobiotic stimulus
cellular response to metal ion
response to starvation
cellular response to inorganic substance
cellular response to nutrient levels
cellular response to extracellular stimulus
protein-containing complex binding
response to xenobiotic stimulus
response to antibiotic
cellular response to external stimulus
response to metal ion
cellular response to drug