BCAS3

Gene Information

Official Symbol: BCAS3
Official Name: BCAS3 microtubule associated cell migration factor
Aliases and Previous Symbols: N/A
Entrez ID: 54828
UniProt: Q9H6U6
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	1/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 18006
Expression level (log2 read counts): 3.78

Expression Distribution

Screen	Score
Asunaprenir 3μM R07 exp336	-1.91
BI-D1870 2μM R04 exp162	2.31

acetyltransferase activator activity
cellular response to estrogen stimulus
negative regulation of focal adhesion assembly
positive regulation of actin cytoskeleton reorganization
regulation of establishment of cell polarity
negative regulation of adherens junction organization
negative regulation of cell junction assembly
regulation of establishment or maintenance of cell polarity
transcriptionally active chromatin
nuclear hormone receptor binding
histone acetyltransferase binding
positive regulation of filopodium assembly
regulation of actin cytoskeleton reorganization
negative regulation of cell-matrix adhesion
beta-tubulin binding
cell periphery
cell leading edge
regulation of filopodium assembly
negative regulation of GTPase activity
intermediate filament cytoskeleton
cytoplasmic microtubule
regulation of focal adhesion assembly
regulation of cell-substrate junction assembly
negative regulation of cell-substrate adhesion
regulation of adherens junction organization
response to estrogen
regulation of cell junction assembly
microtubule organizing center organization
activation of GTPase activity
positive regulation of endothelial cell migration
positive regulation of plasma membrane bounded cell projection assembly
regulation of cell-matrix adhesion
histone binding
Golgi organization
positive regulation of epithelial cell migration
tube formation
positive regulation of intracellular protein transport
regulation of endothelial cell migration
response to starvation
regulation of plasma membrane bounded cell projection assembly