C15orf62

Gene Information

Official Symbol: C15orf62
Official Name: chromosome 15 open reading frame 62
Aliases and Previous Symbols: N/A
Entrez ID: 643338
UniProt: A8K5M9
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
HMS-I2 10μM R06 exp288	-2.08
SB743921 0.001μM R05 exp244	-2
UM131593 0.1μM R01 exp58	-1.81
CI-1040 9.5μM R08 exp472	-1.75
Etoposide 0.3μM R05 exp199	1.87

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 4145
Expression level (log2 read counts): 1.41

Expression Distribution

positive regulation of pseudopodium assembly
regulation of pseudopodium assembly
GTP-Rho binding
Rho protein signal transduction
positive regulation of actin filament polymerization
positive regulation of plasma membrane bounded cell projection assembly
positive regulation of protein polymerization
regulation of cell shape
regulation of actin filament polymerization
regulation of actin polymerization or depolymerization
regulation of actin filament length
positive regulation of supramolecular fiber organization
regulation of plasma membrane bounded cell projection assembly
regulation of cell projection assembly
positive regulation of cytoskeleton organization
regulation of protein polymerization
Ras protein signal transduction
positive regulation of protein complex assembly
regulation of actin filament organization
small GTPase mediated signal transduction
regulation of actin cytoskeleton organization
regulation of supramolecular fiber organization
regulation of cellular component size
positive regulation of cell projection organization
regulation of actin filament-based process
regulation of protein complex assembly
regulation of cell morphogenesis
regulation of anatomical structure size
positive regulation of cellular component biogenesis
regulation of cytoskeleton organization
positive regulation of organelle organization
regulation of plasma membrane bounded cell projection organization
regulation of cell projection organization
regulation of cellular component biogenesis
regulation of anatomical structure morphogenesis
positive regulation of cellular component organization
mitochondrion
regulation of organelle organization
intracellular signal transduction