CAMP

Entrez Summary: N/A
UniProt Summary: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. {ECO:0000269|PubMed:16637646, ECO:0000269|PubMed:18818205}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Cathelicidins
CAP18 C

killing by host of symbiont cells
disruption by host of symbiont cells
killing of cells in other organism involved in symbiotic interaction
specific granule
disruption of cells of other organism involved in symbiotic interaction
innate immune response in mucosa
mucosal immune response
organ or tissue specific immune response
lipopolysaccharide binding
antibacterial humoral response
disruption of cells of other organism
killing of cells of other organism
tertiary granule lumen
specific granule lumen
antimicrobial humoral immune response mediated by antimicrobial peptide
modification by host of symbiont morphology or physiology
interaction with symbiont
defense response to Gram-negative bacterium
cell killing
defense response to Gram-positive bacterium
modification of morphology or physiology of other organism involved in symbiotic interaction
antimicrobial humoral response
modification of morphology or physiology of other organism
defense response to bacterium
humoral immune response
neutrophil degranulation
neutrophil activation involved in immune response
neutrophil mediated immunity
neutrophil activation
granulocyte activation
leukocyte degranulation
myeloid leukocyte mediated immunity
myeloid cell activation involved in immune response
myeloid leukocyte activation
leukocyte activation involved in immune response
cell activation involved in immune response
response to bacterium
regulated exocytosis
innate immune response
leukocyte mediated immunity