CLIC6

Entrez Summary: N/A
UniProt Summary: May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

D4 dopamine receptor binding
D3 dopamine receptor binding
D2 dopamine receptor binding
voltage-gated ion channel activity
chloride channel complex
chloride channel activity
chloride transmembrane transport
chloride transport
inorganic anion transmembrane transport
inorganic anion transport
anion transmembrane transport
regulation of ion transmembrane transport
regulation of transmembrane transport
anion transport
inorganic ion transmembrane transport
regulation of ion transport
ion transmembrane transport
transmembrane transport
ion transport
regulation of transport