CTBS

Entrez Summary: N/A
UniProt Summary: Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N- acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

chitin catabolic process
chitin metabolic process
chitinase activity
glucosamine-containing compound catabolic process
chitin binding
amino sugar catabolic process
oligosaccharide catabolic process
glucosamine-containing compound metabolic process
amino sugar metabolic process
oligosaccharide metabolic process
aminoglycan catabolic process
carbohydrate catabolic process
drug catabolic process
aminoglycan metabolic process
carbohydrate derivative catabolic process
lysosome
carbohydrate metabolic process
drug metabolic process
carbohydrate derivative metabolic process
macromolecule catabolic process
organonitrogen compound catabolic process
extracellular space
organic substance catabolic process
cellular catabolic process