GNPDA1

Entrez Summary: N/A
UniProt Summary: Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

glucosamine catabolic process
glucosamine-6-phosphate deaminase activity
N-acetylglucosamine catabolic process
glucosamine metabolic process
N-acetylneuraminate catabolic process
glucosamine-containing compound catabolic process
UDP-N-acetylglucosamine biosynthetic process
N-acetylneuraminate metabolic process
amino sugar catabolic process
amino sugar biosynthetic process
UDP-N-acetylglucosamine metabolic process
N-acetylglucosamine metabolic process
nucleotide-sugar biosynthetic process
glucosamine-containing compound metabolic process
nucleotide-sugar metabolic process
amino sugar metabolic process
antibiotic catabolic process
antibiotic metabolic process
single fertilization
drug catabolic process
fertilization
carbohydrate derivative catabolic process
carboxylic acid catabolic process
organic acid catabolic process
generation of precursor metabolites and energy
small molecule catabolic process
carbohydrate metabolic process
drug metabolic process
nucleobase-containing small molecule metabolic process
carbohydrate derivative biosynthetic process
sexual reproduction
carboxylic acid metabolic process
multi-organism reproductive process
oxoacid metabolic process
organic acid metabolic process
carbohydrate derivative metabolic process
identical protein binding
nucleobase-containing compound biosynthetic process
heterocycle biosynthetic process
aromatic compound biosynthetic process