HERC6

Official Symbol: HERC6
Official Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
Aliases and Previous Symbols: N/A
Entrez ID: 55008
UniProt: Q8IVU3
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

HECT
RCC1

hematopoietic progenitor cell differentiation
ubiquitin-protein transferase activity
protein polyubiquitination
hemopoiesis
hematopoietic or lymphoid organ development
immune system development
protein ubiquitination
response to bacterium
protein modification by small protein conjugation
protein modification by small protein conjugation or removal
response to other organism
response to external biotic stimulus
response to biotic stimulus