LRFN4

Official Symbol: LRFN4
Official Name: leucine rich repeat and fibronectin type III domain containing 4
Aliases and Previous Symbols: N/A
Entrez ID: 78999
UniProt: Q6PJG9
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Entrez Summary: N/A
UniProt Summary: Promotes neurite outgrowth in hippocampal neurons. May play a role in redistributing DLG4 to the cell periphery (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Calcium Ionophore 0.4μM R07 exp342	1.71
Bisphenol S 100μM R08 exp458	1.83

regulation of postsynaptic density assembly
regulation of postsynaptic specialization assembly
regulation of postsynapse assembly
regulation of excitatory synapse assembly
regulation of postsynaptic density organization
synaptic membrane adhesion
regulation of presynapse assembly
regulation of presynapse organization
integral component of postsynaptic density membrane
GABA-ergic synapse
regulation of postsynapse organization
regulation of synapse assembly
regulation of synapse organization
regulation of organelle assembly
regulation of synapse structure or activity
cell-cell adhesion via plasma-membrane adhesion molecules
synapse organization
glutamatergic synapse
cell-cell adhesion
cell surface
regulation of nervous system development
cell adhesion
biological adhesion
regulation of cellular component biogenesis
regulation of organelle organization