MGST3

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
BI-2536 0.0042μM R03 exp95	1.71
2-Methoxyestradiol 0.55 to 0.75μM on day4 R07 exp311	1.85
PF-06409577 20μM R07 exp389	2

leukotriene-C4 synthase activity
leukotriene biosynthetic process
glutathione peroxidase activity
glutathione derivative metabolic process
glutathione derivative biosynthetic process
glutathione transferase activity
leukotriene metabolic process
icosanoid biosynthetic process
cellular oxidant detoxification
fatty acid derivative biosynthetic process
cellular detoxification
icosanoid metabolic process
detoxification
xenobiotic metabolic process
fatty acid derivative metabolic process
nuclear envelope
sulfur compound biosynthetic process
cellular response to xenobiotic stimulus
cellular response to toxic substance
response to xenobiotic stimulus
carboxylic acid biosynthetic process
organic acid biosynthetic process
sulfur compound metabolic process
response to toxic substance
small molecule biosynthetic process
intracellular membrane-bounded organelle
carboxylic acid metabolic process
endoplasmic reticulum membrane
oxidation-reduction process
response to organonitrogen compound
oxoacid metabolic process
endoplasmic reticulum
organic acid metabolic process
response to nitrogen compound
lipid metabolic process
organonitrogen compound biosynthetic process
small molecule metabolic process
membrane