MTSS1

Entrez Summary: N/A
UniProt Summary: May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

nephron tubule epithelial cell differentiation
epithelial cell proliferation involved in renal tubule morphogenesis
microspike assembly
glomerulus morphogenesis
cellular response to fluid shear stress
actin monomer binding
epithelial cell differentiation involved in kidney development
response to fluid shear stress
cell differentiation involved in kidney development
glomerulus development
endocytic vesicle
renal tubule morphogenesis
nephron tubule development
renal tubule development
epithelial cell proliferation
ruffle
plasma membrane organization
nephron epithelium development
negative regulation of epithelial cell proliferation
nephron development
kidney epithelium development
actin cytoskeleton
kidney development
renal system development
epithelial tube morphogenesis
urogenital system development
regulation of epithelial cell proliferation
signaling receptor binding
endomembrane system organization
morphogenesis of an epithelium
plasma membrane bounded cell projection assembly
cell projection assembly
actin cytoskeleton organization
transmembrane receptor protein tyrosine kinase signaling pathway
cell population proliferation
tissue morphogenesis
actin filament-based process
tube morphogenesis
negative regulation of cell population proliferation
epithelial cell differentiation