PIH1D3

Entrez Summary: N/A
UniProt Summary: Plays a role in cytoplasmic pre-assembly of axonemal dynein. {ECO:0000269|PubMed:28041644}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/694

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/26
bone	0/26
breast	0/30
central nervous system	0/49
cervix	0/4
colorectal	0/17
esophagus	0/11
fibroblast	0/1
gastric	0/14
kidney	0/18
liver	0/19
lung	0/72
lymphocyte	0/16
ovary	0/25
pancreas	0/22
peripheral nervous system	0/15
plasma cell	0/12
prostate	0/1
skin	0/20
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/28
uterus	0/5

Expression Distribution

Screen	Score
Nicotinamide 2000μM R01 exp50	-1.7
PFI-3 10μM R03 exp144	1.88

axonemal dynein complex assembly
cilium movement
axoneme assembly
flagellated sperm motility
sperm motility
microtubule bundle formation
cilium-dependent cell motility
cilium or flagellum-dependent cell motility
chaperone binding
microtubule-based movement
cilium assembly
cilium organization
plasma membrane bounded cell projection assembly
cell projection assembly
microtubule cytoskeleton organization
microtubule-based process
organelle assembly
cellular protein-containing complex assembly
cell motility
localization of cell
cytoskeleton organization
plasma membrane bounded cell projection organization
cell projection organization
locomotion
reproductive process
reproduction
movement of cell or subcellular component
protein-containing complex assembly
protein-containing complex subunit organization