POM121

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Calcipotriol 5μM R08 exp464	-2.04
Adefovir 20μM R07 exp332	-1.77

nuclear localization sequence binding
structural constituent of nuclear pore
tRNA export from nucleus
tRNA-containing ribonucleoprotein complex export from nucleus
tRNA transport
ncRNA export from nucleus
intracellular transport of virus
host cell
transport of virus
protein sumoylation
multi-organism transport
multi-organism localization
nuclear pore
regulation of glycolytic process
regulation of cellular response to heat
regulation of gene silencing by miRNA
regulation of carbohydrate catabolic process
regulation of posttranscriptional gene silencing
regulation of gene silencing by RNA
protein import into nucleus
mRNA export from nucleus
mRNA-containing ribonucleoprotein complex export from nucleus
viral transcription
import into nucleus
regulation of purine nucleotide metabolic process
regulation of nucleotide metabolic process
regulation of ATP metabolic process
ribonucleoprotein complex export from nucleus
ribonucleoprotein complex localization
RNA export from nucleus
regulation of gene silencing
viral gene expression
protein import
protein export from nucleus
mRNA transport
nuclear export
regulation of generation of precursor metabolites and energy
protein localization to nucleus
nuclear envelope
nucleic acid transport