PPP2R2C
Gene Information
- Official Symbol: PPP2R2C
- Official Name: protein phosphatase 2 regulatory subunit Bgamma
- Aliases and Previous Symbols: N/A
- Entrez ID: 5522
- UniProt: Q9Y2T4
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
- UniProt Summary: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 8452
- Expression level (log2 read counts): 1.02
PPP2R2C Expression in NALM6 Cells: 1.02
