RBM4B

Entrez Summary: N/A
UniProt Summary: Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3'-UTR of the PER1 mRNA (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

RRM 1
zf-CCHC

entrainment of circadian clock by photoperiod
photoperiodism
entrainment of circadian clock
mRNA cis splicing, via spliceosome
circadian regulation of gene expression
regulation of alternative mRNA splicing, via spliceosome
regulation of mRNA splicing, via spliceosome
regulation of circadian rhythm
regulation of RNA splicing
regulation of mRNA processing
circadian rhythm
rhythmic process
mRNA splicing, via spliceosome
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
RNA splicing, via transesterification reactions
response to light stimulus
regulation of mRNA metabolic process
regulation of translation
RNA splicing
nuclear speck
regulation of cellular amide metabolic process
response to radiation
mRNA processing
posttranscriptional regulation of gene expression
protein-containing complex
mRNA metabolic process
zinc ion binding
nucleolus
RNA processing
response to abiotic stimulus
RNA binding
RNA metabolic process
positive regulation of gene expression
gene expression