SIK3

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Pkinase
Pkinase Tyr

positive regulation of TORC2 signaling
regulation of TORC2 signaling
positive regulation of TORC1 signaling
tau-protein kinase activity
regulation of TORC1 signaling
positive regulation of TOR signaling
regulation of TOR signaling
magnesium ion binding
protein serine/threonine kinase activity
microtubule cytoskeleton organization
microtubule-based process
protein phosphorylation
positive regulation of intracellular signal transduction
cytoskeleton organization
phosphorylation
ATP binding
positive regulation of signal transduction
intracellular signal transduction
positive regulation of cell communication
positive regulation of signaling
regulation of intracellular signal transduction