SRSF4

Entrez Summary: N/A
UniProt Summary: Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10. {ECO:0000269|PubMed:15009664}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/25
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/15
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/14
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

sequence-specific mRNA binding
negative regulation of mRNA splicing, via spliceosome
negative regulation of RNA splicing
negative regulation of mRNA processing
mRNA cis splicing, via spliceosome
regulation of alternative mRNA splicing, via spliceosome
negative regulation of mRNA metabolic process
mRNA 3-end processing
regulation of mRNA splicing, via spliceosome
mRNA-containing ribonucleoprotein complex export from nucleus
mRNA export from nucleus
ribonucleoprotein complex export from nucleus
ribonucleoprotein complex localization
RNA export from nucleus
RNA 3-end processing
regulation of RNA splicing
regulation of mRNA processing
protein export from nucleus
mRNA transport
nuclear export
RNA transport
nucleic acid transport
establishment of RNA localization
RNA localization
response to insulin
nucleobase-containing compound transport
protein-containing complex localization
nucleocytoplasmic transport
nuclear transport
mRNA splicing, via spliceosome
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
RNA splicing, via transesterification reactions
regulation of mRNA metabolic process
response to peptide hormone
RNA splicing
nuclear speck
response to peptide
mRNA processing
mRNA metabolic process
RNA processing