THEMIS

Gene Information
  • Official Symbol: THEMIS
  • Official Name: thymocyte selection associated
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 387357
  • UniProt: Q8N1K5
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009].
  • UniProt Summary: N/A

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 13186
  • Expression level (log2 read counts): -1.89

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1