TMEM47

Gene Information
  • Official Symbol: TMEM47
  • Official Name: transmembrane protein 47
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 83604
  • UniProt: Q9BQJ4
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly. May regulate F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B. During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin (By similarity). {ECO:0000250|UniProtKB:Q9JJG6, ECO:0000250|UniProtKB:Q9XSV3}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 13692
  • Expression level (log2 read counts): -3.13

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1