TNP2

Gene Information
  • Official Symbol: TNP2
  • Official Name: transition protein 2
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 7142
  • UniProt: Q05952
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. {ECO:0000250|UniProtKB:P11378}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 13706
  • Expression level (log2 read counts): -4.01

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1