VSNL1

Gene Information

Official Symbol: VSNL1
Official Name: visinin like 1
Aliases and Previous Symbols: N/A
Entrez ID: 7447
UniProt: P62760
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner. {ECO:0000250}.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 16467
Expression level (log2 read counts): 0.75

Expression Distribution

positive regulation of insulin secretion involved in cellular response to glucose stimulus
negative regulation of insulin secretion
negative regulation of peptide hormone secretion
regulation of insulin secretion involved in cellular response to glucose stimulus
negative regulation of hormone secretion
positive regulation of insulin secretion
positive regulation of exocytosis
positive regulation of peptide hormone secretion
positive regulation of hormone secretion
negative regulation of protein secretion
negative regulation of peptide secretion
regulation of insulin secretion
negative regulation of protein transport
negative regulation of establishment of protein localization
negative regulation of secretion by cell
regulation of peptide hormone secretion
regulation of exocytosis
negative regulation of secretion
regulation of hormone secretion
positive regulation of protein secretion
positive regulation of peptide secretion
positive regulation of secretion by cell
positive regulation of protein transport
positive regulation of secretion
positive regulation of establishment of protein localization
regulation of protein secretion
negative regulation of transport
regulation of peptide secretion
regulation of hormone levels
regulation of vesicle-mediated transport
regulation of protein transport
calcium ion binding
regulation of peptide transport
regulation of establishment of protein localization
regulation of secretion by cell
regulation of secretion
regulation of cellular localization
positive regulation of transport
regulation of protein localization
negative regulation of cell communication