ZFAND2B

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
iCRT14 30μM R08 exp492	-2.32
6-Thio-2-deoxyguanosine 2μM R06 exp259	-2.21

K48-linked polyubiquitin modification-dependent protein binding
SRP-dependent cotranslational protein targeting to membrane, translocation
regulation of insulin-like growth factor receptor signaling pathway
intracellular protein transmembrane transport
proteasome complex
protein transmembrane transport
ubiquitin binding
SRP-dependent cotranslational protein targeting to membrane
cotranslational protein targeting to membrane
anchored component of membrane
protein targeting to ER
establishment of protein localization to endoplasmic reticulum
protein localization to endoplasmic reticulum
protein targeting to membrane
establishment of protein localization to membrane
proteasome-mediated ubiquitin-dependent protein catabolic process
proteasomal protein catabolic process
protein targeting
establishment of protein localization to organelle
protein localization to membrane
ubiquitin-dependent protein catabolic process
modification-dependent protein catabolic process
modification-dependent macromolecule catabolic process
proteolysis involved in cellular protein catabolic process
cellular protein catabolic process
protein catabolic process
protein localization to organelle
zinc ion binding
cellular macromolecule catabolic process
endoplasmic reticulum membrane
intracellular protein transport
endoplasmic reticulum
macromolecule catabolic process
organonitrogen compound catabolic process
proteolysis
transmembrane transport
protein transport
intracellular transport
peptide transport
amide transport