ZFYVE28

Gene Information

Official Symbol: ZFYVE28
Official Name: zinc finger FYVE-type containing 28
Aliases and Previous Symbols: N/A
Entrez ID: 57732
UniProt: Q9HCC9
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 10655
Expression level (log2 read counts): 3.27

Expression Distribution

negative regulation of epidermal growth factor-activated receptor activity
regulation of epidermal growth factor-activated receptor activity
negative regulation of protein tyrosine kinase activity
phosphatidylinositol-3-phosphate binding
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of peptidyl-tyrosine phosphorylation
negative regulation of ERBB signaling pathway
negative regulation of signaling receptor activity
regulation of epidermal growth factor receptor signaling pathway
regulation of protein tyrosine kinase activity
regulation of ERBB signaling pathway
early endosome membrane
regulation of signaling receptor activity
negative regulation of protein kinase activity
negative regulation of kinase activity
regulation of peptidyl-tyrosine phosphorylation
negative regulation of transferase activity
negative regulation of protein phosphorylation
negative regulation of phosphorylation
negative regulation of phosphate metabolic process
negative regulation of phosphorus metabolic process
negative regulation of protein modification process
negative regulation of catalytic activity
regulation of protein kinase activity
regulation of kinase activity
regulation of transferase activity
negative regulation of cellular protein metabolic process
negative regulation of protein metabolic process
negative regulation of molecular function
negative regulation of signal transduction
negative regulation of cell communication
negative regulation of signaling
regulation of protein phosphorylation
regulation of phosphorylation
negative regulation of response to stimulus
regulation of phosphate metabolic process
regulation of phosphorus metabolic process
regulation of protein modification process