The Human Chemical-Genetic Interaction Map Project - human_genes:j
https://crispr.tyerslab.com/
2026-04-04T20:03:50+00:00The Human Chemical-Genetic Interaction Map Project
https://crispr.tyerslab.com/
https://crispr.tyerslab.com/_media/wiki/dokuwiki.svgtext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JAG1
https://crispr.tyerslab.com/human_genes/j/jag1?rev=1765415987&do=diff
JAG1
Gene Information
* Official Symbol: JAG1
* Official Name: jagged canonical Notch ligand 1
* Aliases and Previous Symbols: N/A
* Entrez ID: 182
* UniProt: P78504
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JAG2
https://crispr.tyerslab.com/human_genes/j/jag2?rev=1765415987&do=diff
JAG2
Gene Information
* Official Symbol: JAG2
* Official Name: jagged canonical Notch ligand 2
* Aliases and Previous Symbols: N/A
* Entrez ID: 3714
* UniProt: Q9Y219
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JAGN1
https://crispr.tyerslab.com/human_genes/j/jagn1?rev=1765415987&do=diff
JAGN1
Gene Information
* Official Symbol: JAGN1
* Official Name: jagunal homolog 1
* Aliases and Previous Symbols: N/A
* Entrez ID: 84522
* UniProt: Q8N5M9
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summary: The protein encoded by this gene is a transmembrane protein. It functions in the early secretory pathway and is necessary for neutrophil differentiation and survival. Mutations in this gene result in severe congen…text/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JAK1
https://crispr.tyerslab.com/human_genes/j/jak1?rev=1765415987&do=diff
JAK1
Gene Information
* Official Symbol: JAK1
* Official Name: Janus kinase 1
* Aliases and Previous Symbols: N/A
* Entrez ID: 3716
* UniProt: P23458
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summary: This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. Th…text/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JAK2
https://crispr.tyerslab.com/human_genes/j/jak2?rev=1765415987&do=diff
JAK2
Gene Information
* Official Symbol: JAK2
* Official Name: Janus kinase 2
* Aliases and Previous Symbols: N/A
* Entrez ID: 3717
* UniProt: O60674
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summary: This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for re…text/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JAK3
https://crispr.tyerslab.com/human_genes/j/jak3?rev=1765415987&do=diff
JAK3
Gene Information
* Official Symbol: JAK3
* Official Name: Janus kinase 3
* Aliases and Previous Symbols: N/A
* Entrez ID: 3718
* UniProt: P52333
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summary: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells a…text/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JAKMIP1
https://crispr.tyerslab.com/human_genes/j/jakmip1?rev=1765415987&do=diff
JAKMIP1
Gene Information
* Official Symbol: JAKMIP1
* Official Name: janus kinase and microtubule interacting protein 1
* Aliases and Previous Symbols: N/A
* Entrez ID: 152789
* UniProt: Q96N16
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JAKMIP2
https://crispr.tyerslab.com/human_genes/j/jakmip2?rev=1765415987&do=diff
JAKMIP2
Gene Information
* Official Symbol: JAKMIP2
* Official Name: janus kinase and microtubule interacting protein 2
* Aliases and Previous Symbols: N/A
* Entrez ID: 9832
* UniProt: Q96AA8
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JAKMIP3
https://crispr.tyerslab.com/human_genes/j/jakmip3?rev=1765415987&do=diff
JAKMIP3
Gene Information
* Official Symbol: JAKMIP3
* Official Name: Janus kinase and microtubule interacting protein 3
* Aliases and Previous Symbols: N/A
* Entrez ID: 282973
* UniProt: Q5VZ66
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JAM2
https://crispr.tyerslab.com/human_genes/j/jam2?rev=1765415987&do=diff
JAM2
Gene Information
* Official Symbol: JAM2
* Official Name: junctional adhesion molecule 2
* Aliases and Previous Symbols: N/A
* Entrez ID: 58494
* UniProt: P57087
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JAM3
https://crispr.tyerslab.com/human_genes/j/jam3?rev=1765415987&do=diff
JAM3
Gene Information
* Official Symbol: JAM3
* Official Name: junctional adhesion molecule 3
* Aliases and Previous Symbols: N/A
* Entrez ID: 83700
* UniProt: Q9BX67
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JARID2
https://crispr.tyerslab.com/human_genes/j/jarid2?rev=1765415987&do=diff
JARID2
Gene Information
* Official Symbol: JARID2
* Official Name: jumonji and AT-rich interaction domain containing 2
* Aliases and Previous Symbols: N/A
* Entrez ID: 3720
* UniProt: Q92833
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JAZF1
https://crispr.tyerslab.com/human_genes/j/jazf1?rev=1765415987&do=diff
JAZF1
Gene Information
* Official Symbol: JAZF1
* Official Name: JAZF zinc finger 1
* Aliases and Previous Symbols: N/A
* Entrez ID: 221895
* UniProt: Q86VZ6
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summary: This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Al…text/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JDP2
https://crispr.tyerslab.com/human_genes/j/jdp2?rev=1765415987&do=diff
JDP2
Gene Information
* Official Symbol: JDP2
* Official Name: Jun dimerization protein 2
* Aliases and Previous Symbols: N/A
* Entrez ID: 122953
* UniProt: Q8WYK2
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summarytext/html2026-01-08T03:36:58+00:00Anonymous (anonymous@undisclosed.example.com)JHDM1D
https://crispr.tyerslab.com/human_genes/j/jhdm1d?rev=1767843418&do=diff
JHDM1D
Gene Information
* Official Symbol: KDM7A
* Official Name: lysine demethylase 7A
* Aliases and Previous Symbols: N/A
* Entrez ID: 80853
* UniProt: Q6ZMT4
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JKAMP
https://crispr.tyerslab.com/human_genes/j/jkamp?rev=1765415987&do=diff
JKAMP
Gene Information
* Official Symbol: JKAMP
* Official Name: JNK1/MAPK8 associated membrane protein
* Aliases and Previous Symbols: N/A
* Entrez ID: 51528
* UniProt: Q9P055
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
*text/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JMJD1C
https://crispr.tyerslab.com/human_genes/j/jmjd1c?rev=1765415987&do=diff
JMJD1C
Gene Information
* Official Symbol: JMJD1C
* Official Name: jumonji domain containing 1C
* Aliases and Previous Symbols: N/A
* Entrez ID: 221037
* UniProt: Q15652
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JMJD4
https://crispr.tyerslab.com/human_genes/j/jmjd4?rev=1765415987&do=diff
JMJD4
Gene Information
* Official Symbol: JMJD4
* Official Name: jumonji domain containing 4
* Aliases and Previous Symbols: N/A
* Entrez ID: 65094
* UniProt: Q9H9V9
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JMJD6
https://crispr.tyerslab.com/human_genes/j/jmjd6?rev=1765415987&do=diff
JMJD6
Gene Information
* Official Symbol: JMJD6
* Official Name: jumonji domain containing 6, arginine demethylase and lysine hydroxylase
* Aliases and Previous Symbols: N/A
* Entrez ID: 23210
* UniProt: Q6NYC1
* Interactions: BioGRID
* PubMed articlestext/html2026-01-08T03:36:58+00:00Anonymous (anonymous@undisclosed.example.com)JMJD7-PLA2G4B
https://crispr.tyerslab.com/human_genes/j/jmjd7-pla2g4b?rev=1767843418&do=diff
JMJD7-PLA2G4B
Gene Information
* Official Symbol: N/A
* Official Name: N/A
* Aliases and Previous Symbols: N/A
* Entrez ID: 8681
* UniProt: N/A
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: N/A
Function Summary
* Entrez Summary: N/Atext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JMJD7
https://crispr.tyerslab.com/human_genes/j/jmjd7?rev=1765415987&do=diff
JMJD7
Gene Information
* Official Symbol: JMJD7
* Official Name: jumonji domain containing 7
* Aliases and Previous Symbols: N/A
* Entrez ID: 100137047
* UniProt: P0C870
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JMJD8
https://crispr.tyerslab.com/human_genes/j/jmjd8?rev=1765415987&do=diff
JMJD8
Gene Information
* Official Symbol: JMJD8
* Official Name: jumonji domain containing 8
* Aliases and Previous Symbols: N/A
* Entrez ID: 339123
* UniProt: Q96S16
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: N/A
Function Summary
* Entrez Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JMY
https://crispr.tyerslab.com/human_genes/j/jmy?rev=1765415987&do=diff
JMY
Gene Information
* Official Symbol: JMY
* Official Name: junction mediating and regulatory protein, p53 cofactor
* Aliases and Previous Symbols: N/A
* Entrez ID: 133746
* UniProt: Q8N9B5
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JOSD1
https://crispr.tyerslab.com/human_genes/j/josd1?rev=1765415987&do=diff
JOSD1
Gene Information
* Official Symbol: JOSD1
* Official Name: Josephin domain containing 1
* Aliases and Previous Symbols: N/A
* Entrez ID: 9929
* UniProt: Q15040
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JOSD2
https://crispr.tyerslab.com/human_genes/j/josd2?rev=1765415987&do=diff
JOSD2
Gene Information
* Official Symbol: JOSD2
* Official Name: Josephin domain containing 2
* Aliases and Previous Symbols: N/A
* Entrez ID: 126119
* UniProt: Q8TAC2
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JPH1
https://crispr.tyerslab.com/human_genes/j/jph1?rev=1765415987&do=diff
JPH1
Gene Information
* Official Symbol: JPH1
* Official Name: junctophilin 1
* Aliases and Previous Symbols: N/A
* Entrez ID: 56704
* UniProt: Q9HDC5
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summary: Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The p…text/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JPH2
https://crispr.tyerslab.com/human_genes/j/jph2?rev=1765415987&do=diff
JPH2
Gene Information
* Official Symbol: JPH2
* Official Name: junctophilin 2
* Aliases and Previous Symbols: N/A
* Entrez ID: 57158
* UniProt: Q9BR39
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summary: Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The p…text/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JPH3
https://crispr.tyerslab.com/human_genes/j/jph3?rev=1765415987&do=diff
JPH3
Gene Information
* Official Symbol: JPH3
* Official Name: junctophilin 3
* Aliases and Previous Symbols: N/A
* Entrez ID: 57338
* UniProt: Q8WXH2
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summary: Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The p…text/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JPH4
https://crispr.tyerslab.com/human_genes/j/jph4?rev=1765415987&do=diff
JPH4
Gene Information
* Official Symbol: JPH4
* Official Name: junctophilin 4
* Aliases and Previous Symbols: N/A
* Entrez ID: 84502
* UniProt: Q96JJ6
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summary: N/A
*text/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JRK
https://crispr.tyerslab.com/human_genes/j/jrk?rev=1765415987&do=diff
JRK
Gene Information
* Official Symbol: JRK
* Official Name: Jrk helix-turn-helix protein
* Aliases and Previous Symbols: N/A
* Entrez ID: 8629
* UniProt: O75564
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JRKL
https://crispr.tyerslab.com/human_genes/j/jrkl?rev=1765415987&do=diff
JRKL
Gene Information
* Official Symbol: JRKL
* Official Name: JRK like
* Aliases and Previous Symbols: N/A
* Entrez ID: 8690
* UniProt: Q9Y4A0
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summary: N/A
* UniProt Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JSRP1
https://crispr.tyerslab.com/human_genes/j/jsrp1?rev=1765415987&do=diff
JSRP1
Gene Information
* Official Symbol: JSRP1
* Official Name: junctional sarcoplasmic reticulum protein 1
* Aliases and Previous Symbols: N/A
* Entrez ID: 126306
* UniProt: Q96MG2
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JTB
https://crispr.tyerslab.com/human_genes/j/jtb?rev=1765415987&do=diff
JTB
Gene Information
* Official Symbol: JTB
* Official Name: jumping translocation breakpoint
* Aliases and Previous Symbols: N/A
* Entrez ID: 10899
* UniProt: O76095
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JUN
https://crispr.tyerslab.com/human_genes/j/jun?rev=1765415987&do=diff
JUN
Gene Information
* Official Symbol: JUN
* Official Name: Jun proto-oncogene, AP-1 transcription factor subunit
* Aliases and Previous Symbols: N/A
* Entrez ID: 3725
* UniProt: P05412
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JUNB
https://crispr.tyerslab.com/human_genes/j/junb?rev=1765415987&do=diff
JUNB
Gene Information
* Official Symbol: JUNB
* Official Name: JunB proto-oncogene, AP-1 transcription factor subunit
* Aliases and Previous Symbols: N/A
* Entrez ID: 3726
* UniProt: P17275
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JUND
https://crispr.tyerslab.com/human_genes/j/jund?rev=1765415987&do=diff
JUND
Gene Information
* Official Symbol: JUND
* Official Name: JunD proto-oncogene, AP-1 transcription factor subunit
* Aliases and Previous Symbols: N/A
* Entrez ID: 3727
* UniProt: P17535
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summarytext/html2025-12-11T01:19:47+00:00Anonymous (anonymous@undisclosed.example.com)JUP
https://crispr.tyerslab.com/human_genes/j/jup?rev=1765415987&do=diff
JUP
Gene Information
* Official Symbol: JUP
* Official Name: junction plakoglobin
* Aliases and Previous Symbols: N/A
* Entrez ID: 3728
* UniProt: P14923
* Interactions: BioGRID
* PubMed articles: Open PubMed
* OMIM: Open OMIM
Function Summary
* Entrez Summary: This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins a…