C16orf59 [The Human Chemical-Genetic Interaction Map Project]

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======= C16orf59 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: TEDC2
  * **<color #00a2e8>Official Name</color>**: tubulin epsilon and delta complex 2
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=80178|80178]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q7L2K0|Q7L2K0]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=C16orf59&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20C16orf59|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp349|Cytochalasin-B 5μM R07 exp349]]|4.16|
|[[:results:exp374|Latrunculin-B 10μM R07 exp374]]|4.5|
|[[:results:exp414|Tozasertib 0.1μM R07 exp414]]|5.65|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:c:c14orf80|C14orf80]]|0.799|
|[[:human genes:t:tubd1|TUBD1]]|0.715|
|[[:human genes:t:tube1|TUBE1]]|0.681|
|[[:human genes:p:pidd|PIDD]]|0.659|
|[[:human genes:c:c2cd3|C2CD3]]|0.634|
|[[:human genes:c:cradd|CRADD]]|0.624|
|[[:human genes:c:cep120|CEP120]]|0.624|
|[[:human genes:o:odf2|ODF2]]|0.616|
|[[:human genes:c:casp2|CASP2]]|0.595|
|[[:human genes:k:kiaa0753|KIAA0753]]|0.589|
|[[:human genes:p:pibf1|PIBF1]]|0.572|
|[[:human genes:c:ccdc41|CCDC41]]|0.565|
|[[:human genes:n:nin|NIN]]|0.557|
|[[:human genes:o:ofd1|OFD1]]|0.551|
|[[:human genes:a:ankrd26|ANKRD26]]|0.548|
|[[:human genes:r:rttn|RTTN]]|0.537|
|[[:human genes:s:sclt1|SCLT1]]|0.525|
|[[:human genes:c:cep44|CEP44]]|0.516|
|[[:human genes:c:cep76|CEP76]]|0.499|
|[[:human genes:h:hyls1|HYLS1]]|0.481|
|[[:human genes:b:bub3|BUB3]]|0.476|
|[[:human genes:f:fgfr1op|FGFR1OP]]|0.474|
|[[:human genes:c:cep128|CEP128]]|0.469|
|[[:human genes:f:fopnl|FOPNL]]|0.45|
|[[:human genes:s:srp9|SRP9]]|0.437|
|[[:human genes:c:cep152|CEP152]]|0.425|
|[[:human genes:c:cep78|CEP78]]|0.419|
|[[:human genes:w:wdr1|WDR1]]|0.416|
|[[:human genes:d:ddx42|DDX42]]|0.413|
|[[:human genes:s:srp14|SRP14]]|0.411|
|[[:human genes:t:tsen54|TSEN54]]|0.402|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 22/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|1/28|
|blood|3/28|
|bone|1/26|
|breast|0/33|
|central nervous system|2/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|2/21|
|liver|0/20|
|lung|3/75|
|lymphocyte|0/16|
|ovary|1/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|1/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|1/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 847
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 5.01 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='C16ORF59 Expression in NALM6 Cells: 5.01'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>