C16orf72 [The Human Chemical-Genetic Interaction Map Project]

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======= C16orf72 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: C16orf72
  * **<color #00a2e8>Official Name</color>**: chromosome 16 open reading frame 72
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=29035|29035]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q14CZ0|Q14CZ0]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=C16orf72&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20C16orf72|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp102|Nifuroxazide 5μM R03 exp102]]|-2.49|
|[[:results:exp535|Trimetrexate 0.03μM R08 exp535]]|-2.44|
|[[:results:exp288|HMS-I2 10μM R06 exp288]]|-2.4|
|[[:results:exp299|Talazoparib 0.006μM R06 exp299]]|-2.27|
|[[:results:exp264|Arsenate 40μM R06 exp264]]|-2.16|
|[[:results:exp444|THZ531 0.225μM R08 exp444]]|-2.05|
|[[:results:exp78|Pterostilbene 16μM R02 exp78]]|-1.99|
|[[:results:exp329|Hydroxyurea 100μM R07 exp329]]|-1.85|
|[[:results:exp410|THZ531 0.11 to 0.125μM on day4 R07 exp410]]|-1.85|
|[[:results:exp455|Benzoate 10000μM R08 exp455]]|-1.83|
|[[:results:exp303|39°C R06 exp303]]|-1.77|
|[[:results:exp120|Dimethyl-Sulfoxide 1pc R03 exp120]]|-1.76|
|[[:results:exp413|THZ531 0.11 to 0.175μM on day4 R07 exp413]]|-1.71|
|[[:results:exp134|MS023 2μM R03 exp134]]|-1.7|
|[[:results:exp409|THZ531 0.11μM R07 exp409]]|-1.7|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:u:ubr5|UBR5]]|0.427|
|[[:human genes:p:prr12|PRR12]]|0.414|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 63/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|2/28|
|blood|1/28|
|bone|0/26|
|breast|6/33|
|central nervous system|3/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|8/21|
|liver|0/20|
|lung|7/75|
|lymphocyte|0/16|
|ovary|3/26|
|pancreas|1/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|1/1|
|skin|4/24|
|soft tissue|3/9|
|thyroid|0/2|
|upper aerodigestive|5/22|
|urinary tract|2/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1488
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 7.67 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='C16orf72 Expression in NALM6 Cells: 10.48'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>