C7orf26 [The Human Chemical-Genetic Interaction Map Project]

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======= C7orf26 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: C7orf26
  * **<color #00a2e8>Official Name</color>**: chromosome 7 open reading frame 26
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=79034|79034]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q96N11|Q96N11]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=C7orf26&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20C7orf26|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp84|UM0125461 0.74μM R02 exp84]]|-2.83|
|[[:results:exp416|Tubacin 1.6μM R07 exp416]]|-2.56|
|[[:results:exp243|S-trityl-L-cysteine 0.5μM R05 exp243]]|-2.26|
|[[:results:exp122|Golgicide-A 4μM R03 exp122]]|-2.09|
|[[:results:exp190|Vincristine 0.0005μM R04 exp190]]|-2.07|
|[[:results:exp179|Combretastatin A4 0.002 to 0.003μM day4 R04 exp179]]|-1.89|
|[[:results:exp75|MK-1775 0.32μM R02 exp75]]|-1.79|
|[[:results:exp287|HMS-I2 5μM R06 exp287]]|-1.75|
|[[:results:exp504|MK2206 4μM R08 exp504]]|-1.73|
|[[:results:exp175|3-Bromopyruvate 7μM R04 exp175]]|-1.72|
|[[:results:exp13|Chloramphenicol 20μM R00 exp13]]|1.71|
|[[:results:exp143|Phenformin 20μM R03 exp143]]|1.74|
|[[:results:exp241|QNZ 0.01μM R05 exp241]]|1.75|
|[[:results:exp461|BS-181 20μM R08 exp461]]|1.77|
|[[:results:exp510|Nicotine 3000μM R08 exp510]]|1.79|
|[[:results:exp36|TRAIL 50ng/ml R00 exp36]]|1.8|
|[[:results:exp468|CB-5083 0.4μM R08 exp468]]|1.81|
|[[:results:exp259|6-Thio-2-deoxyguanosine 2μM R06 exp259]]|1.9|
|[[:results:exp25|Oligomycin-A 2μM R00 exp25]]|1.9|
|[[:results:exp414|Tozasertib 0.1μM R07 exp414]]|1.9|
|[[:results:exp191|Hypoxia 5%O2 R04 exp191]]|1.91|
|[[:results:exp492|iCRT14 30μM R08 exp492]]|1.96|
|[[:results:exp85|UM0129480 7μM R02 exp85]]|1.99|
|[[:results:exp68|Clomiphene 4.4μM R02 exp68]]|2.01|
|[[:results:exp67|BVD-523 15μM R02 exp67]]|2.02|
|[[:results:exp450|Artemisinin 50μM R08 exp450]]|2.1|
|[[:results:exp330|5-Azacytidine 2μM R07 exp330]]|2.11|
|[[:results:exp474|CR131-b 0.005μM R08 exp474]]|2.15|
|[[:results:exp65|Mubritinib 0.2μM R02 exp65]]|2.21|
|[[:results:exp431|Rotenone 0.07μM R08 exp431]]|2.22|
|[[:results:exp111|R-DABN 8μM R03 exp111]]|2.27|
|[[:results:exp80|RO-3307 4.7μM R02 exp80]]|2.29|
|[[:results:exp294|Nutlin-3A 1.6μM R06 exp294]]|2.32|
|[[:results:exp244|SB743921 0.001μM R05 exp244]]|2.39|
|[[:results:exp35|TRAIL 5ng/ml R00 exp35]]|2.44|
|[[:results:exp98|BI-6727 0.04μM R03 exp98]]|2.45|
|[[:results:exp24|Nocodazole 0.2μM R00 exp24]]|2.47|
|[[:results:exp116|AICAR 240μM R03 exp116]]|2.56|
|[[:results:exp93|DABN racemic mixture R03 exp93]]|2.67|
|[[:results:exp211|AICAR 240μM R05 exp211]]|2.7|
|[[:results:exp226|Cerivastatin 0.15μM R05 exp226]]|2.72|
|[[:results:exp48|Mubritinib 0.2μM R01 exp48]]|2.87|
|[[:results:exp535|Trimetrexate 0.03μM R08 exp535]]|2.95|
|[[:results:exp94|Nocodazole 0.1μM R03 exp94]]|2.98|
|[[:results:exp282|Fluvastatin 2.2μM R06 exp282]]|3.29|
|[[:results:exp33|Rotenone 2μM R00 exp33]]|3.35|
|[[:results:exp439|QNZ 0.01μM R08 exp439]]|3.57|
|[[:results:exp374|Latrunculin-B 10μM R07 exp374]]|3.71|
|[[:results:exp135|MS023 7μM R03 exp135]]|4.02|
|[[:results:exp134|MS023 2μM R03 exp134]]|4.87|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:a:asun|ASUN]]|0.819|
|[[:human genes:i:ints10|INTS10]]|0.798|
|[[:human genes:v:vwa9|VWA9]]|0.62|
|[[:human genes:d:dph3|DPH3]]|0.453|
|[[:human genes:c:ctu2|CTU2]]|0.452|
|[[:human genes:i:ipmk|IPMK]]|0.446|
|[[:human genes:u:urm1|URM1]]|0.433|
|[[:human genes:c:ctu1|CTU1]]|0.43|
|[[:human genes:r:rbm26|RBM26]]|0.427|
|[[:human genes:i:itpk1|ITPK1]]|0.422|
|[[:human genes:a:acsl3|ACSL3]]|0.42|
|[[:human genes:u:uba5|UBA5]]|0.416|
|[[:human genes:e:elp6|ELP6]]|0.416|
|[[:human genes:e:elp2|ELP2]]|0.413|
|[[:human genes:m:mocs3|MOCS3]]|0.412|
|[[:human genes:a:alkbh8|ALKBH8]]|0.41|
|[[:human genes:p:pqbp1|PQBP1]]|0.41|
|[[:human genes:n:nr2c2ap|NR2C2AP]]|0.409|
|[[:human genes:e:elp3|ELP3]]|0.403|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 20/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|2/26|
|breast|0/33|
|central nervous system|2/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|1/16|
|kidney|2/21|
|liver|1/20|
|lung|3/75|
|lymphocyte|0/16|
|ovary|2/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|3/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|1/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1530
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 5.11 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='C7orf26 Expression in NALM6 Cells: 8.74'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>