CCDC64B [The Human Chemical-Genetic Interaction Map Project]

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======= CCDC64B =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: BICDL2
  * **<color #00a2e8>Official Name</color>**: BICD family like cargo adaptor 2
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=146439|146439]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/A1A5D9|A1A5D9]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=CCDC64B&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20CCDC64B|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/617003|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|Golgi to secretory granule transport|
|vesicle transport along microtubule|
|vesicle cytoskeletal trafficking|
|organelle transport along microtubule|
|Rab GTPase binding|
|transport along microtubule|
|establishment of vesicle localization|
|cytoskeleton-dependent intracellular transport|
|microtubule-based transport|
|vesicle localization|
|microtubule-based movement|
|establishment of organelle localization|
|organelle localization|
|microtubule-based process|
|intracellular transport|
|movement of cell or subcellular component|
|establishment of localization in cell|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp190|Vincristine 0.0005μM R04 exp190]]|1.8|
|[[:results:exp15|Cycloheximide 0.2μM R00 exp15]]|1.91|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:v:vasn|VASN]]|0.545|
|[[:human genes:d:dock6|DOCK6]]|0.531|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.515|
|[[:human genes:c:c14orf93|C14orf93]]|0.514|
|[[:human genes:n:nupl1|NUPL1]]|0.513|
|[[:human genes:c:chd4|CHD4]]|0.513|
|[[:human genes:p:pan3|PAN3]]|0.502|
|[[:human genes:a:aamp|AAMP]]|0.497|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.494|
|[[:human genes:t:tbc1d3c|TBC1D3C]]|0.494|
|[[:human genes:g:golga6a|GOLGA6A]]|0.49|
|[[:human genes:w:wdr87|WDR87]]|0.49|
|[[:human genes:c:cbwd3|CBWD3]]|0.49|
|[[:human genes:c:ccna2|CCNA2]]|0.486|
|[[:human genes:p:psmd3|PSMD3]]|0.485|
|[[:human genes:x:xylt2|XYLT2]]|0.484|
|[[:human genes:d:disp2|DISP2]]|0.481|
|[[:human genes:r:rps2|RPS2]]|0.48|
|[[:human genes:c:cdca3|CDCA3]]|0.47|
|[[:human genes:f:fam160a1|FAM160A1]]|0.469|
|[[:human genes:t:tbc1d3|TBC1D3]]|0.469|
|[[:human genes:c:cbwd6|CBWD6]]|0.469|
|[[:human genes:p:psmc1|PSMC1]]|0.469|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.468|
|[[:human genes:g:golga8o|GOLGA8O]]|0.467|
|[[:human genes:a:acsf2|ACSF2]]|0.465|
|[[:human genes:k:kctd17|KCTD17]]|0.465|
|[[:human genes:p:pole|POLE]]|0.462|
|[[:human genes:o:orc1|ORC1]]|0.462|
|[[:human genes:t:tceb3c|TCEB3C]]|0.461|
|[[:human genes:d:dtl|DTL]]|0.461|
|[[:human genes:c:copg1|COPG1]]|0.461|
|[[:human genes:g:golga6b|GOLGA6B]]|0.46|
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.459|
|[[:human genes:c:cbwd5|CBWD5]]|0.459|
|[[:human genes:o:orc6|ORC6]]|0.455|
|[[:human genes:t:tfip11|TFIP11]]|0.455|
|[[:human genes:z:zfand5|ZFAND5]]|0.455|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.453|
|[[:human genes:p:psma6|PSMA6]]|0.452|
|[[:human genes:e:exosc9|EXOSC9]]|0.451|
|[[:human genes:s:smg7|SMG7]]|0.451|
|[[:human genes:d:ddtl|DDTL]]|0.448|
|[[:human genes:z:znf655|ZNF655]]|0.447|
|[[:human genes:p:psmd11|PSMD11]]|0.446|
|[[:human genes:c:cdc6|CDC6]]|0.445|
|[[:human genes:s:ssh2|SSH2]]|0.443|
|[[:human genes:p:pwp2|PWP2]]|0.443|
|[[:human genes:h:hivep3|HIVEP3]]|0.443|
|[[:human genes:m:mt1e|MT1E]]|0.443|
|[[:human genes:s:sap30bp|SAP30BP]]|0.442|
|[[:human genes:h:hist2h2bf|HIST2H2BF]]|0.441|
|[[:human genes:n:nsf|NSF]]|0.44|
|[[:human genes:w:wdr43|WDR43]]|0.439|
|[[:human genes:c:cope|COPE]]|0.438|
|[[:human genes:p:pan2|PAN2]]|0.437|
|[[:human genes:n:nup160|NUP160]]|0.437|
|[[:human genes:r:rad51|RAD51]]|0.436|
|[[:human genes:c:ciapin1|CIAPIN1]]|0.435|
|[[:human genes:c:copa|COPA]]|0.435|
|[[:human genes:m:myo18a|MYO18A]]|0.434|
|[[:human genes:a:ankle2|ANKLE2]]|0.433|
|[[:human genes:s:snrpa1|SNRPA1]]|0.432|
|[[:human genes:a:ankle1|ANKLE1]]|0.432|
|[[:human genes:o:ogfr|OGFR]]|0.431|
|[[:human genes:t:ticrr|TICRR]]|0.431|
|[[:human genes:h:hap1|HAP1]]|0.431|
|[[:human genes:n:numa1|NUMA1]]|0.431|
|[[:human genes:c:cmya5|CMYA5]]|0.43|
|[[:human genes:p:psmc2|PSMC2]]|0.429|
|[[:human genes:c:col2a1|COL2A1]]|0.429|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.429|
|[[:human genes:s:supt5h|SUPT5H]]|0.429|
|[[:human genes:c:cdc73|CDC73]]|0.429|
|[[:human genes:t:tbc1d3e|TBC1D3E]]|0.428|
|[[:human genes:p:psmd1|PSMD1]]|0.428|
|[[:human genes:g:gosr2|GOSR2]]|0.428|
|[[:human genes:f:fbxw9|FBXW9]]|0.428|
|[[:human genes:h:hist1h2be|HIST1H2BE]]|0.428|
|[[:human genes:t:tbc1d3l|TBC1D3L]]|0.427|
|[[:human genes:t:tbc1d3i|TBC1D3I]]|0.427|
|[[:human genes:t:tbc1d3k|TBC1D3K]]|0.427|
|[[:human genes:p:ppm1d|PPM1D]]|0.426|
|[[:human genes:r:rps12|RPS12]]|0.426|
|[[:human genes:t:twistnb|TWISTNB]]|0.425|
|[[:human genes:s:slc4a1|SLC4A1]]|0.424|
|[[:human genes:r:ran|RAN]]|0.424|
|[[:human genes:i:itga2b|ITGA2B]]|0.424|
|[[:human genes:a:arhgef15|ARHGEF15]]|0.424|
|[[:human genes:e:exosc3|EXOSC3]]|0.423|
|[[:human genes:t:tsg101|TSG101]]|0.423|
|[[:human genes:n:napa|NAPA]]|0.422|
|[[:human genes:p:ppfia4|PPFIA4]]|0.422|
|[[:human genes:z:znf830|ZNF830]]|0.421|
|[[:human genes:s:sec13|SEC13]]|0.421|
|[[:human genes:s:sh3bp1|SH3BP1]]|0.42|
|[[:human genes:c:ccdc116|CCDC116]]|0.42|
|[[:human genes:r:rrp1|RRP1]]|0.42|
|[[:human genes:g:golga6l4|GOLGA6L4]]|0.419|
|[[:human genes:m:madcam1|MADCAM1]]|0.416|
|[[:human genes:k:krt78|KRT78]]|0.415|
|[[:human genes:u:usp36|USP36]]|0.415|
|[[:human genes:t:tpx2|TPX2]]|0.414|
|[[:human genes:n:nup85|NUP85]]|0.414|
|[[:human genes:u:ubl5|UBL5]]|0.414|
|[[:human genes:r:rpl35|RPL35]]|0.414|
|[[:human genes:k:krt2|KRT2]]|0.413|
|[[:human genes:c:cln6|CLN6]]|0.413|
|[[:human genes:s:sema6b|SEMA6B]]|0.412|
|[[:human genes:m:mcm7|MCM7]]|0.412|
|[[:human genes:z:znf106|ZNF106]]|0.411|
|[[:human genes:p:psmb2|PSMB2]]|0.41|
|[[:human genes:c:cox8a|COX8A]]|0.41|
|[[:human genes:r:rps19bp1|RPS19BP1]]|0.409|
|[[:human genes:n:nol10|NOL10]]|0.409|
|[[:human genes:l:lad1|LAD1]]|0.408|
|[[:human genes:b:bcl2l1|BCL2L1]]|0.408|
|[[:human genes:c:cdh24|CDH24]]|0.407|
|[[:human genes:c:cactin|CACTIN]]|0.407|
|[[:human genes:n:nop16|NOP16]]|0.407|
|[[:human genes:c:cnot1|CNOT1]]|0.406|
|[[:human genes:c:c2orf27b|C2orf27B]]|0.405|
|[[:human genes:c:copb1|COPB1]]|0.404|
|[[:human genes:i:ik|IK]]|0.404|
|[[:human genes:k:kif3c|KIF3C]]|0.404|
|[[:human genes:a:atp13a1|ATP13A1]]|0.404|
|[[:human genes:c:cdca5|CDCA5]]|0.404|
|[[:human genes:a:abhd8|ABHD8]]|0.403|
|[[:human genes:g:gprin2|GPRIN2]]|0.403|
|[[:human genes:c:cgb2|CGB2]]|0.403|
|[[:human genes:r:rnpc3|RNPC3]]|0.403|
|[[:human genes:e:exd1|EXD1]]|0.402|
|[[:human genes:p:plekha4|PLEKHA4]]|0.402|
|[[:human genes:r:rpl14|RPL14]]|0.402|
|[[:human genes:m:mms22l|MMS22L]]|0.401|
|[[:human genes:c:chaf1a|CHAF1A]]|0.401|
|[[:human genes:b:bid|BID]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1902
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 0.05 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='CCDC64B Expression in NALM6 Cells: 0.05'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>