CEP44 [The Human Chemical-Genetic Interaction Map Project]

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======= CEP44 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: CEP44
  * **<color #00a2e8>Official Name</color>**: centrosomal protein 44
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=80817|80817]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q9C0F1|Q9C0F1]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=CEP44&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20CEP44|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/620217|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|spindle pole|
|midbody|
|centrosome|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp238|Parthenolide 2.5μM R05 exp238]]|-1.98|
|[[:results:exp215|Colchicine 0.009μM R05 exp215]]|-1.9|
|[[:results:exp49|NFN1 0.1μM R01 exp49]]|-1.9|
|[[:results:exp46|HMS-I1 1μM R01 exp46]]|-1.83|
|[[:results:exp228|Demecolcine 0.03μM R05 exp228]]|-1.72|
|[[:results:exp60|Vinblastine 0.002μM R01 exp60]]|-1.71|
|[[:results:exp80|RO-3307 4.7μM R02 exp80]]|1.78|
|[[:results:exp533|TNF-alpha 44ng/ml R08 exp533]]|1.79|
|[[:results:exp500|LY2090314 0.003μM R08 exp500 no dilution day6]]|1.8|
|[[:results:exp431|Rotenone 0.07μM R08 exp431]]|1.99|
|[[:results:exp501|Methotrexate 0.01μM R08 exp501]]|2.03|
|[[:results:exp22|MLN-4924 2μM R00 exp22]]|2.31|
|[[:results:exp515|PU-H71 1μM R08 exp515]]|2.37|
|[[:results:exp487|Hinokiflavone 12μM R08 exp487]]|2.62|
|[[:results:exp349|Cytochalasin-B 5μM R07 exp349]]|3.93|
|[[:results:exp414|Tozasertib 0.1μM R07 exp414]]|4.15|
|[[:results:exp374|Latrunculin-B 10μM R07 exp374]]|5.54|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:c:c14orf80|C14orf80]]|0.622|
|[[:human genes:t:tubd1|TUBD1]]|0.579|
|[[:human genes:c:cep120|CEP120]]|0.547|
|[[:human genes:c:casp2|CASP2]]|0.521|
|[[:human genes:c:c16orf59|C16orf59]]|0.516|
|[[:human genes:c:ccdc41|CCDC41]]|0.515|
|[[:human genes:p:pidd|PIDD]]|0.494|
|[[:human genes:c:c2cd3|C2CD3]]|0.494|
|[[:human genes:t:tube1|TUBE1]]|0.49|
|[[:human genes:k:kiaa0753|KIAA0753]]|0.469|
|[[:human genes:c:cradd|CRADD]]|0.464|
|[[:human genes:f:fgfr1op|FGFR1OP]]|0.445|
|[[:human genes:o:odf2|ODF2]]|0.445|
|[[:human genes:k:kiaa1731|KIAA1731]]|0.437|
|[[:human genes:c:cep76|CEP76]]|0.435|
|[[:human genes:p:pibf1|PIBF1]]|0.434|
|[[:human genes:a:ankrd26|ANKRD26]]|0.423|
|[[:human genes:c:cep128|CEP128]]|0.422|
|[[:human genes:t:tkt|TKT]]|0.42|
|[[:human genes:s:srp9|SRP9]]|0.401|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 14918
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 5.14 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='CEP44 Expression in NALM6 Cells: 5.14'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>