CTAGE9 [The Human Chemical-Genetic Interaction Map Project]

This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong.
======= CTAGE9 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: CTAGE9
  * **<color #00a2e8>Official Name</color>**: CTAGE family member 9
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=643854|643854]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/A4FU28|A4FU28]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=CTAGE9&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20CTAGE9|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|vesicle cargo loading|
|endoplasmic reticulum exit site|
|protein secretion|
|establishment of protein localization to extracellular region|
|protein localization to extracellular region|
|peptide secretion|
|endoplasmic reticulum to Golgi vesicle-mediated transport|
|Golgi vesicle transport|
|endoplasmic reticulum membrane|
|secretion by cell|
|export from cell|
|secretion|
|protein transport|
|intracellular transport|
|peptide transport|
|amide transport|
|establishment of protein localization|
|establishment of localization in cell|
|nitrogen compound transport|
|vesicle-mediated transport|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp401|SNS-032 25μM R07 exp401]]|-2.24|
|[[:results:exp102|Nifuroxazide 5μM R03 exp102]]|1.72|
|[[:results:exp239|PFI-2 4μM R05 exp239]]|1.92|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:g:golga6l1|GOLGA6L1]]|0.555|
|[[:human genes:c:cbwd3|CBWD3]]|0.48|
|[[:human genes:p:psmb4|PSMB4]]|0.469|
|[[:human genes:v:vps28|VPS28]]|0.458|
|[[:human genes:c:cbwd6|CBWD6]]|0.457|
|[[:human genes:c:chd4|CHD4]]|0.449|
|[[:human genes:c:cbwd5|CBWD5]]|0.447|
|[[:human genes:p:prim1|PRIM1]]|0.446|
|[[:human genes:t:tp53tg3c|TP53TG3C]]|0.44|
|[[:human genes:t:tp53tg3b|TP53TG3B]]|0.44|
|[[:human genes:t:tp53tg3|TP53TG3]]|0.44|
|[[:human genes:p:pdcd11|PDCD11]]|0.439|
|[[:human genes:p:pan3|PAN3]]|0.437|
|[[:human genes:a:atp6v1b2|ATP6V1B2]]|0.436|
|[[:human genes:t:tsg101|TSG101]]|0.43|
|[[:human genes:h:hgc6.3|HGC6.3]]|0.429|
|[[:human genes:n:nsf|NSF]]|0.427|
|[[:human genes:s:supt6h|SUPT6H]]|0.425|
|[[:human genes:a:atp6v1c1|ATP6V1C1]]|0.421|
|[[:human genes:t:tceb3c|TCEB3C]]|0.421|
|[[:human genes:a:ankle2|ANKLE2]]|0.42|
|[[:human genes:p:polr2d|POLR2D]]|0.418|
|[[:human genes:c:chaf1a|CHAF1A]]|0.414|
|[[:human genes:p:psmc1|PSMC1]]|0.414|
|[[:human genes:p:psma6|PSMA6]]|0.413|
|[[:human genes:d:ddtl|DDTL]]|0.412|
|[[:human genes:z:znf830|ZNF830]]|0.411|
|[[:human genes:c:copg1|COPG1]]|0.411|
|[[:human genes:a:atp6v1a|ATP6V1A]]|0.41|
|[[:human genes:d:ddt|DDT]]|0.41|
|[[:human genes:v:vps54|VPS54]]|0.409|
|[[:human genes:r:rpl35|RPL35]]|0.408|
|[[:human genes:u:upf1|UPF1]]|0.408|
|[[:human genes:c:ccna2|CCNA2]]|0.407|
|[[:human genes:p:psmc2|PSMC2]]|0.407|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.406|
|[[:human genes:p:psma7|PSMA7]]|0.405|
|[[:human genes:c:col2a1|COL2A1]]|0.405|
|[[:human genes:w:wdr75|WDR75]]|0.405|
|[[:human genes:r:rpl30|RPL30]]|0.403|
|[[:human genes:g:golga6l6|GOLGA6L6]]|0.401|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 2/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|1/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1507
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: -1.66 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='CTAGE9 Expression in NALM6 Cells: -1.66'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>