CXorf38 [The Human Chemical-Genetic Interaction Map Project]

This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong.
======= CXorf38 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: CXorf38
  * **<color #00a2e8>Official Name</color>**: chromosome X open reading frame 38
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=159013|159013]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q8TB03|Q8TB03]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=CXorf38&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20CXorf38|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/301117|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp131|L-74142 5μM R03 exp131]]|-1.9|
|[[:results:exp94|Nocodazole 0.1μM R03 exp94]]|-1.8|
|[[:results:exp342|Calcium Ionophore 0.4μM R07 exp342]]|1.7|
|[[:results:exp354|Diepoxybutane 3μM R07 exp354]]|1.86|
|[[:results:exp335|Aminopterin 0.005μM R07 exp335]]|2.05|
|[[:results:exp36|TRAIL 50ng/ml R00 exp36]]|7.25|
|[[:results:exp35|TRAIL 5ng/ml R00 exp35]]|7.25|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:f:fadd|FADD]]|0.617|
|[[:human genes:c:casp8|CASP8]]|0.615|
|[[:human genes:t:tnfrsf10b|TNFRSF10B]]|0.598|
|[[:human genes:h:hnrnpl|HNRNPL]]|0.525|
|[[:human genes:c:casp3|CASP3]]|0.506|
|[[:human genes:c:ccnc|CCNC]]|0.46|
|[[:human genes:s:smarce1|SMARCE1]]|0.441|
|[[:human genes:i:ikzf2|IKZF2]]|0.437|
|[[:human genes:c:creb1|CREB1]]|0.424|
|[[:human genes:e:elavl1|ELAVL1]]|0.417|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/694
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/26|
|bone|0/26|
|breast|0/30|
|central nervous system|0/49|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/11|
|fibroblast|0/1|
|gastric|0/14|
|kidney|0/18|
|liver|0/19|
|lung|0/72|
|lymphocyte|0/16|
|ovary|0/25|
|pancreas|0/22|
|peripheral nervous system|0/15|
|plasma cell|0/12|
|prostate|0/1|
|skin|0/20|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/28|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 5637
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 5.39 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='CXorf38 Expression in NALM6 Cells: 8.93'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>