GCNT7 [The Human Chemical-Genetic Interaction Map Project]

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======= GCNT7 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: GCNT7
  * **<color #00a2e8>Official Name</color>**: glucosaminyl (N-acetyl) transferase family member 7
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=140687|140687]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q6ZNI0|Q6ZNI0]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=GCNT7&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20GCNT7|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**:  Glycosyltransferase. {ECO:0000250}.

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|Branch|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|acetylglucosaminyltransferase activity|
|protein glycosylation|
|macromolecule glycosylation|
|glycosylation|
|glycoprotein biosynthetic process|
|glycoprotein metabolic process|
|Golgi membrane|
|carbohydrate derivative biosynthetic process|
|carbohydrate derivative metabolic process|
|organonitrogen compound biosynthetic process|
|cellular macromolecule biosynthetic process|
|macromolecule biosynthetic process|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp365|I-BRD9 4μM R07 exp365]]|-1.96|
|[[:results:exp392|PT-1 25μM R07 exp392]]|-1.83|
|[[:results:exp400|Senexin-A 25μM R07 exp400]]|-1.83|
|[[:results:exp113|1-Methyl-nicotinamide-chloride 1000μM R03 exp113]]|-1.7|
|[[:results:exp271|CCT251545 0.2μM R06 exp271]]|1.7|
|[[:results:exp238|Parthenolide 2.5μM R05 exp238]]|1.71|
|[[:results:exp246|UM0011500 10μM R05 exp246]]|1.71|
|[[:results:exp289|Hydroxyurea 15μM R06 exp289]]|1.74|
|[[:results:exp175|3-Bromopyruvate 7μM R04 exp175]]|1.78|
|[[:results:exp184|Ixabepilone 0.004 to 0.005μM on day4 R04 exp184]]|1.88|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 16918
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: -0.41 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='GCNT7 Expression in NALM6 Cells: -0.41'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>