GOLGA6A [The Human Chemical-Genetic Interaction Map Project]

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======= GOLGA6A =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: GOLGA6A
  * **<color #00a2e8>Official Name</color>**: golgin A6 family member A
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=342096|342096]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q9NYA3|Q9NYA3]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=GOLGA6A&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20GOLGA6A|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/610288|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|Golgi cis cisterna|
|cis-Golgi network|
|Golgi cisterna membrane|
|spindle assembly|
|Golgi organization|
|spindle organization|
|endomembrane system organization|
|microtubule cytoskeleton organization|
|microtubule-based process|
|organelle assembly|
|Golgi apparatus|
|cell cycle process|
|cytoskeleton organization|
|cell cycle|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp527|Tanespimycin 14μM R08 exp527]]|-1.81|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:t:tceb3c|TCEB3C]]|0.52|
|[[:human genes:v:vasn|VASN]]|0.516|
|[[:human genes:o:orc6|ORC6]]|0.515|
|[[:human genes:c:cope|COPE]]|0.508|
|[[:human genes:o:orc1|ORC1]]|0.498|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.497|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.495|
|[[:human genes:c:ccdc64b|CCDC64B]]|0.49|
|[[:human genes:c:chd4|CHD4]]|0.489|
|[[:human genes:t:tbc1d3|TBC1D3]]|0.489|
|[[:human genes:t:ticrr|TICRR]]|0.487|
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.487|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.486|
|[[:human genes:k:kctd17|KCTD17]]|0.476|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.474|
|[[:human genes:t:tfip11|TFIP11]]|0.474|
|[[:human genes:s:slc4a1|SLC4A1]]|0.473|
|[[:human genes:p:psmd3|PSMD3]]|0.473|
|[[:human genes:a:akirin2|AKIRIN2]]|0.47|
|[[:human genes:t:tbc1d3c|TBC1D3C]]|0.47|
|[[:human genes:p:psma6|PSMA6]]|0.47|
|[[:human genes:r:rad51|RAD51]]|0.469|
|[[:human genes:p:pole|POLE]]|0.469|
|[[:human genes:t:tp53tg3b|TP53TG3B]]|0.468|
|[[:human genes:t:tp53tg3|TP53TG3]]|0.467|
|[[:human genes:t:tp53tg3c|TP53TG3C]]|0.467|
|[[:human genes:t:twistnb|TWISTNB]]|0.467|
|[[:human genes:s:supt6h|SUPT6H]]|0.463|
|[[:human genes:c:cmya5|CMYA5]]|0.462|
|[[:human genes:a:aamp|AAMP]]|0.46|
|[[:human genes:r:rpl9|RPL9]]|0.459|
|[[:human genes:s:sap30bp|SAP30BP]]|0.457|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.457|
|[[:human genes:s:syt9|SYT9]]|0.45|
|[[:human genes:n:nupl1|NUPL1]]|0.448|
|[[:human genes:d:dnttip2|DNTTIP2]]|0.448|
|[[:human genes:c:c14orf93|C14orf93]]|0.446|
|[[:human genes:d:dtl|DTL]]|0.446|
|[[:human genes:c:cbwd6|CBWD6]]|0.446|
|[[:human genes:c:cbwd3|CBWD3]]|0.444|
|[[:human genes:p:psmc1|PSMC1]]|0.443|
|[[:human genes:c:ccna2|CCNA2]]|0.434|
|[[:human genes:r:rps19bp1|RPS19BP1]]|0.433|
|[[:human genes:s:sf3a3|SF3A3]]|0.432|
|[[:human genes:d:dock6|DOCK6]]|0.432|
|[[:human genes:s:sec13|SEC13]]|0.432|
|[[:human genes:r:rrn3|RRN3]]|0.43|
|[[:human genes:g:golga8o|GOLGA8O]]|0.429|
|[[:human genes:o:ogfr|OGFR]]|0.429|
|[[:human genes:c:cdc45|CDC45]]|0.427|
|[[:human genes:r:rps2|RPS2]]|0.426|
|[[:human genes:o:osbp|OSBP]]|0.423|
|[[:human genes:l:lrr1|LRR1]]|0.423|
|[[:human genes:r:riok2|RIOK2]]|0.422|
|[[:human genes:s:sprr2b|SPRR2B]]|0.419|
|[[:human genes:p:psmb4|PSMB4]]|0.419|
|[[:human genes:r:rps3a|RPS3A]]|0.418|
|[[:human genes:m:mylk3|MYLK3]]|0.417|
|[[:human genes:r:rpl7l1|RPL7L1]]|0.416|
|[[:human genes:i:ik|IK]]|0.415|
|[[:human genes:c:cdc6|CDC6]]|0.415|
|[[:human genes:p:psmb2|PSMB2]]|0.415|
|[[:human genes:s:sf3a2|SF3A2]]|0.414|
|[[:human genes:e:elmod3|ELMOD3]]|0.414|
|[[:human genes:c:chaf1a|CHAF1A]]|0.413|
|[[:human genes:f:fbxw9|FBXW9]]|0.413|
|[[:human genes:c:cbwd5|CBWD5]]|0.412|
|[[:human genes:a:acsf2|ACSF2]]|0.411|
|[[:human genes:e:exosc5|EXOSC5]]|0.409|
|[[:human genes:s:slc6a17|SLC6A17]]|0.409|
|[[:human genes:n:nup160|NUP160]]|0.409|
|[[:human genes:m:mt1e|MT1E]]|0.409|
|[[:human genes:n:npipb5|NPIPB5]]|0.409|
|[[:human genes:g:gosr2|GOSR2]]|0.408|
|[[:human genes:a:ankle2|ANKLE2]]|0.408|
|[[:human genes:g:gon4l|GON4L]]|0.408|
|[[:human genes:p:psmd6|PSMD6]]|0.405|
|[[:human genes:i:igfn1|IGFN1]]|0.405|
|[[:human genes:r:rps12|RPS12]]|0.405|
|[[:human genes:w:wdr87|WDR87]]|0.405|
|[[:human genes:s:stil|STIL]]|0.405|
|[[:human genes:a:aqr|AQR]]|0.404|
|[[:human genes:c:copg1|COPG1]]|0.404|
|[[:human genes:a:aatf|AATF]]|0.404|
|[[:human genes:n:nup205|NUP205]]|0.403|
|[[:human genes:c:copa|COPA]]|0.403|
|[[:human genes:t:tm7sf2|TM7SF2]]|0.403|
|[[:human genes:s:slc5a5|SLC5A5]]|0.402|
|[[:human genes:c:cln6|CLN6]]|0.402|
|[[:human genes:f:fam160a1|FAM160A1]]|0.401|
|[[:human genes:n:napa|NAPA]]|0.401|
|[[:human genes:z:znf830|ZNF830]]|0.4|
|[[:human genes:r:rad21|RAD21]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 35/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|1/28|
|blood|2/28|
|bone|0/26|
|breast|2/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|1/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|2/16|
|kidney|0/21|
|liver|1/20|
|lung|7/75|
|lymphocyte|2/16|
|ovary|2/26|
|pancreas|2/24|
|peripheral nervous system|2/16|
|plasma cell|2/15|
|prostate|1/1|
|skin|0/24|
|soft tissue|1/9|
|thyroid|0/2|
|upper aerodigestive|1/22|
|urinary tract|1/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 2178
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 0.66 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='GOLGA6A Expression in NALM6 Cells: 0.66'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>