GOLGA6B [The Human Chemical-Genetic Interaction Map Project]

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======= GOLGA6B =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: GOLGA6B
  * **<color #00a2e8>Official Name</color>**: golgin A6 family member B
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=55889|55889]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/A6NDN3|A6NDN3]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=GOLGA6B&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20GOLGA6B|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|Golgi cis cisterna|
|cis-Golgi network|
|Golgi cisterna membrane|
|spindle assembly|
|Golgi organization|
|spindle organization|
|endomembrane system organization|
|microtubule cytoskeleton organization|
|microtubule-based process|
|organelle assembly|
|Golgi apparatus|
|cell cycle process|
|cytoskeleton organization|
|cell cycle|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp527|Tanespimycin 14μM R08 exp527]]|-2.03|
|[[:results:exp19|Etoposide 1μM R00 exp19]]|-1.91|
|[[:results:exp113|1-Methyl-nicotinamide-chloride 1000μM R03 exp113]]|1.75|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:h:hgc6.3|HGC6.3]]|0.657|
|[[:human genes:t:tbc1d3|TBC1D3]]|0.479|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.467|
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.466|
|[[:human genes:r:rps7|RPS7]]|0.464|
|[[:human genes:c:ccdc64b|CCDC64B]]|0.46|
|[[:human genes:r:rps2|RPS2]]|0.46|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.458|
|[[:human genes:p:psma6|PSMA6]]|0.455|
|[[:human genes:t:twistnb|TWISTNB]]|0.455|
|[[:human genes:t:tbc1d3i|TBC1D3I]]|0.445|
|[[:human genes:t:tbc1d3k|TBC1D3K]]|0.445|
|[[:human genes:c:chd4|CHD4]]|0.445|
|[[:human genes:t:tbc1d3e|TBC1D3E]]|0.445|
|[[:human genes:s:sap30bp|SAP30BP]]|0.444|
|[[:human genes:t:tbc1d3l|TBC1D3L]]|0.444|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.441|
|[[:human genes:o:ogfr|OGFR]]|0.44|
|[[:human genes:t:tfip11|TFIP11]]|0.44|
|[[:human genes:v:vps54|VPS54]]|0.44|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.439|
|[[:human genes:t:tceb3c|TCEB3C]]|0.435|
|[[:human genes:r:rps3a|RPS3A]]|0.433|
|[[:human genes:t:tbc1d3c|TBC1D3C]]|0.43|
|[[:human genes:p:pla2g4f|PLA2G4F]]|0.43|
|[[:human genes:c:cln6|CLN6]]|0.428|
|[[:human genes:p:prpf8|PRPF8]]|0.425|
|[[:human genes:r:rad51|RAD51]]|0.423|
|[[:human genes:c:cmya5|CMYA5]]|0.421|
|[[:human genes:a:aatf|AATF]]|0.419|
|[[:human genes:c:ccna2|CCNA2]]|0.419|
|[[:human genes:p:psmd3|PSMD3]]|0.417|
|[[:human genes:n:napa|NAPA]]|0.413|
|[[:human genes:o:orc6|ORC6]]|0.412|
|[[:human genes:r:rps12|RPS12]]|0.407|
|[[:human genes:r:rpl9|RPL9]]|0.407|
|[[:human genes:u:utp3|UTP3]]|0.405|
|[[:human genes:v:vasn|VASN]]|0.405|
|[[:human genes:t:timeless|TIMELESS]]|0.405|
|[[:human genes:h:hivep3|HIVEP3]]|0.404|
|[[:human genes:p:polr2d|POLR2D]]|0.402|
|[[:human genes:c:cdc45|CDC45]]|0.401|
|[[:human genes:r:rpl35|RPL35]]|0.401|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 1/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|1/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 2311
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: -0.64 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='GOLGA6B Expression in NALM6 Cells: -0.64'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>