GOLGA8O [The Human Chemical-Genetic Interaction Map Project]

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======= GOLGA8O =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: GOLGA8O
  * **<color #00a2e8>Official Name</color>**: golgin A8 family member O
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=728047|728047]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/A6NCC3|A6NCC3]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=GOLGA8O&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20GOLGA8O|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|Golgi cis cisterna|
|cis-Golgi network|
|Golgi cisterna membrane|
|spindle assembly|
|Golgi organization|
|spindle organization|
|endomembrane system organization|
|microtubule cytoskeleton organization|
|microtubule-based process|
|organelle assembly|
|Golgi apparatus|
|cell cycle process|
|cytoskeleton organization|
|cell cycle|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp17|DABN 20μM R00 exp17]]|-1.7|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:c:c14orf93|C14orf93]]|0.556|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.526|
|[[:human genes:p:psmb4|PSMB4]]|0.525|
|[[:human genes:t:tceb3c|TCEB3C]]|0.514|
|[[:human genes:c:cope|COPE]]|0.51|
|[[:human genes:r:rpl6|RPL6]]|0.506|
|[[:human genes:v:vasn|VASN]]|0.503|
|[[:human genes:n:npipb5|NPIPB5]]|0.5|
|[[:human genes:r:rps19|RPS19]]|0.495|
|[[:human genes:d:ddtl|DDTL]]|0.494|
|[[:human genes:r:rps9|RPS9]]|0.491|
|[[:human genes:c:cbwd3|CBWD3]]|0.49|
|[[:human genes:s:s1pr4|S1PR4]]|0.489|
|[[:human genes:k:krt78|KRT78]]|0.488|
|[[:human genes:r:rps2|RPS2]]|0.486|
|[[:human genes:s:slc6a17|SLC6A17]]|0.486|
|[[:human genes:r:rps3a|RPS3A]]|0.484|
|[[:human genes:p:pola2|POLA2]]|0.483|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.483|
|[[:human genes:p:parp3|PARP3]]|0.483|
|[[:human genes:p:prim1|PRIM1]]|0.48|
|[[:human genes:g:golga6l6|GOLGA6L6]]|0.478|
|[[:human genes:r:rps12|RPS12]]|0.478|
|[[:human genes:n:nupl1|NUPL1]]|0.476|
|[[:human genes:s:supt5h|SUPT5H]]|0.476|
|[[:human genes:n:npipb8|NPIPB8]]|0.475|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.475|
|[[:human genes:c:chd4|CHD4]]|0.473|
|[[:human genes:c:col2a1|COL2A1]]|0.472|
|[[:human genes:r:rad51|RAD51]]|0.472|
|[[:human genes:p:psma6|PSMA6]]|0.471|
|[[:human genes:c:ccdc116|CCDC116]]|0.469|
|[[:human genes:p:pwp2|PWP2]]|0.468|
|[[:human genes:t:tp53tg3b|TP53TG3B]]|0.467|
|[[:human genes:w:wdr87|WDR87]]|0.467|
|[[:human genes:c:ccdc64b|CCDC64B]]|0.467|
|[[:human genes:c:copa|COPA]]|0.466|
|[[:human genes:t:tp53tg3c|TP53TG3C]]|0.465|
|[[:human genes:t:tp53tg3|TP53TG3]]|0.465|
|[[:human genes:w:wdr75|WDR75]]|0.464|
|[[:human genes:r:rps5|RPS5]]|0.462|
|[[:human genes:h:hist2h3c|HIST2H3C]]|0.462|
|[[:human genes:h:hist2h3a|HIST2H3A]]|0.462|
|[[:human genes:t:tpx2|TPX2]]|0.461|
|[[:human genes:a:aamp|AAMP]]|0.46|
|[[:human genes:t:ticrr|TICRR]]|0.459|
|[[:human genes:s:slc4a1|SLC4A1]]|0.459|
|[[:human genes:p:paf1|PAF1]]|0.458|
|[[:human genes:t:twistnb|TWISTNB]]|0.458|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.458|
|[[:human genes:m:myo1h|MYO1H]]|0.458|
|[[:human genes:p:psmb1|PSMB1]]|0.457|
|[[:human genes:p:psmd11|PSMD11]]|0.456|
|[[:human genes:c:cbwd6|CBWD6]]|0.456|
|[[:human genes:g:golga6l3|GOLGA6L3]]|0.455|
|[[:human genes:m:myh7b|MYH7B]]|0.455|
|[[:human genes:o:orc1|ORC1]]|0.455|
|[[:human genes:c:cdc6|CDC6]]|0.454|
|[[:human genes:p:pan2|PAN2]]|0.454|
|[[:human genes:s:snrpa1|SNRPA1]]|0.454|
|[[:human genes:c:cgb2|CGB2]]|0.453|
|[[:human genes:s:scgb1c1|SCGB1C1]]|0.452|
|[[:human genes:t:tbc1d3|TBC1D3]]|0.452|
|[[:human genes:p:psmc1|PSMC1]]|0.451|
|[[:human genes:p:psmb3|PSMB3]]|0.451|
|[[:human genes:p:psmc2|PSMC2]]|0.45|
|[[:human genes:p:plk4|PLK4]]|0.449|
|[[:human genes:c:cbwd5|CBWD5]]|0.449|
|[[:human genes:c:cdc73|CDC73]]|0.448|
|[[:human genes:c:cep192|CEP192]]|0.447|
|[[:human genes:c:cactin|CACTIN]]|0.447|
|[[:human genes:i:ints5|INTS5]]|0.445|
|[[:human genes:p:pan3|PAN3]]|0.445|
|[[:human genes:r:rnf113a|RNF113A]]|0.445|
|[[:human genes:m:mt1e|MT1E]]|0.445|
|[[:human genes:g:golga6l1|GOLGA6L1]]|0.445|
|[[:human genes:p:psmc5|PSMC5]]|0.445|
|[[:human genes:r:rpsa|RPSA]]|0.443|
|[[:human genes:p:pola1|POLA1]]|0.442|
|[[:human genes:p:pole|POLE]]|0.442|
|[[:human genes:m:mcm7|MCM7]]|0.441|
|[[:human genes:m:mdm2|MDM2]]|0.44|
|[[:human genes:b:bysl|BYSL]]|0.439|
|[[:human genes:t:tuba8|TUBA8]]|0.438|
|[[:human genes:s:ssh2|SSH2]]|0.438|
|[[:human genes:t:tbc1d3c|TBC1D3C]]|0.437|
|[[:human genes:i:iscu|ISCU]]|0.437|
|[[:human genes:c:ctage4|CTAGE4]]|0.436|
|[[:human genes:s:sf3a1|SF3A1]]|0.436|
|[[:human genes:k:kctd17|KCTD17]]|0.436|
|[[:human genes:n:nol10|NOL10]]|0.436|
|[[:human genes:e:eif4a3|EIF4A3]]|0.436|
|[[:human genes:d:dock6|DOCK6]]|0.434|
|[[:human genes:r:rpl35|RPL35]]|0.433|
|[[:human genes:d:dido1|DIDO1]]|0.432|
|[[:human genes:c:ccna2|CCNA2]]|0.432|
|[[:human genes:c:chaf1a|CHAF1A]]|0.432|
|[[:human genes:i:ik|IK]]|0.431|
|[[:human genes:e:egr2|EGR2]]|0.431|
|[[:human genes:d:disp2|DISP2]]|0.431|
|[[:human genes:d:ddx41|DDX41]]|0.431|
|[[:human genes:n:napa|NAPA]]|0.431|
|[[:human genes:a:akt1s1|AKT1S1]]|0.43|
|[[:human genes:n:nup133|NUP133]]|0.43|
|[[:human genes:p:psmd6|PSMD6]]|0.43|
|[[:human genes:k:krt2|KRT2]]|0.43|
|[[:human genes:p:psmd7|PSMD7]]|0.43|
|[[:human genes:d:ddt|DDT]]|0.429|
|[[:human genes:z:zfand5|ZFAND5]]|0.429|
|[[:human genes:g:golga6a|GOLGA6A]]|0.429|
|[[:human genes:g:gid4|GID4]]|0.428|
|[[:human genes:t:tsg101|TSG101]]|0.427|
|[[:human genes:p:psmd2|PSMD2]]|0.425|
|[[:human genes:h:hgc6.3|HGC6.3]]|0.424|
|[[:human genes:e:exosc4|EXOSC4]]|0.424|
|[[:human genes:v:vps28|VPS28]]|0.423|
|[[:human genes:h:hist2h3d|HIST2H3D]]|0.423|
|[[:human genes:s:skiv2l2|SKIV2L2]]|0.422|
|[[:human genes:a:aldh1b1|ALDH1B1]]|0.422|
|[[:human genes:a:acsf2|ACSF2]]|0.422|
|[[:human genes:s:supt6h|SUPT6H]]|0.421|
|[[:human genes:c:cdca3|CDCA3]]|0.42|
|[[:human genes:h:hist1h4b|HIST1H4B]]|0.42|
|[[:human genes:p:psmc4|PSMC4]]|0.42|
|[[:human genes:o:or11h6|OR11H6]]|0.42|
|[[:human genes:p:polr2i|POLR2I]]|0.42|
|[[:human genes:z:znf830|ZNF830]]|0.419|
|[[:human genes:t:tbc1d3e|TBC1D3E]]|0.418|
|[[:human genes:t:tbc1d3i|TBC1D3I]]|0.418|
|[[:human genes:k:kif3c|KIF3C]]|0.418|
|[[:human genes:t:tbc1d3l|TBC1D3L]]|0.418|
|[[:human genes:t:tbc1d3k|TBC1D3K]]|0.418|
|[[:human genes:r:rbbp5|RBBP5]]|0.418|
|[[:human genes:c:cdc45|CDC45]]|0.417|
|[[:human genes:l:lrr1|LRR1]]|0.417|
|[[:human genes:z:znf655|ZNF655]]|0.417|
|[[:human genes:a:ankle2|ANKLE2]]|0.416|
|[[:human genes:a:atp6ap1|ATP6AP1]]|0.416|
|[[:human genes:s:stil|STIL]]|0.415|
|[[:human genes:r:rps7|RPS7]]|0.415|
|[[:human genes:t:tfip11|TFIP11]]|0.414|
|[[:human genes:r:rrp7a|RRP7A]]|0.413|
|[[:human genes:f:fam231c|FAM231C]]|0.413|
|[[:human genes:g:golga8j|GOLGA8J]]|0.413|
|[[:human genes:e:ebna1bp2|EBNA1BP2]]|0.413|
|[[:human genes:f:fam231a|FAM231A]]|0.412|
|[[:human genes:s:sart1|SART1]]|0.412|
|[[:human genes:m:mms22l|MMS22L]]|0.412|
|[[:human genes:e:exosc5|EXOSC5]]|0.412|
|[[:human genes:r:rad21|RAD21]]|0.412|
|[[:human genes:e:exosc9|EXOSC9]]|0.412|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.411|
|[[:human genes:n:nol12|NOL12]]|0.411|
|[[:human genes:p:psmb2|PSMB2]]|0.411|
|[[:human genes:c:ctr9|CTR9]]|0.41|
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.41|
|[[:human genes:r:rps20|RPS20]]|0.41|
|[[:human genes:c:copg1|COPG1]]|0.41|
|[[:human genes:t:trim52|TRIM52]]|0.409|
|[[:human genes:e:exosc6|EXOSC6]]|0.409|
|[[:human genes:s:sec13|SEC13]]|0.408|
|[[:human genes:n:nbpf10|NBPF10]]|0.408|
|[[:human genes:n:ndc80|NDC80]]|0.405|
|[[:human genes:o:or10g3|OR10G3]]|0.404|
|[[:human genes:h:hist1h2be|HIST1H2BE]]|0.404|
|[[:human genes:g:golga6l4|GOLGA6L4]]|0.403|
|[[:human genes:x:xab2|XAB2]]|0.403|
|[[:human genes:r:rps28|RPS28]]|0.403|
|[[:human genes:s:sap30bp|SAP30BP]]|0.402|
|[[:human genes:p:psma7|PSMA7]]|0.402|
|[[:human genes:h:hap1|HAP1]]|0.402|
|[[:human genes:c:chmp2a|CHMP2A]]|0.402|
|[[:human genes:o:ogfr|OGFR]]|0.402|
|[[:human genes:x:xylt2|XYLT2]]|0.402|
|[[:human genes:g:gar1|GAR1]]|0.401|
|[[:human genes:u:upf1|UPF1]]|0.4|
|[[:human genes:d:ddx56|DDX56]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 0/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1506
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: -1.19 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='GOLGA8O Expression in NALM6 Cells: -1.19'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>