LOC100505679 [The Human Chemical-Genetic Interaction Map Project]

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======= LOC100505679 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: N/A
  * **<color #00a2e8>Official Name</color>**: N/A
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: N/A
  * **<color #00a2e8>UniProt</color>**: N/A
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=LOC100505679&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20LOC100505679|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='default' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
No Pfam Domain information is available for this gene.
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp521|Salinomycin 3.5μM R08 exp521]]|-2.08|
|[[:results:exp277|Curcumin 6.5μM R06 exp277]]|-2.01|
|[[:results:exp275|Citral 75μM R06 exp275]]|-1.88|
|[[:results:exp247|UM0130462 0.025 to 0.035μM day4 R05 exp247]]|-1.87|
|[[:results:exp59|UMK57 1μM R01 exp59]]|1.7|
|[[:results:exp494|Isoniazid 100μM R08 exp494]]|1.71|
|[[:results:exp35|TRAIL 5ng/ml R00 exp35]]|1.71|
|[[:results:exp45|Docetaxel 0.002μM R01 exp45]]|1.74|
|[[:results:exp115|A-366 10μM R03 exp115]]|1.8|
|[[:results:exp61|YM155 0.0002μM R01 exp61]]|1.8|
|[[:results:exp60|Vinblastine 0.002μM R01 exp60]]|1.83|
|[[:results:exp242|Radicicol 0.16μM R05 exp242]]|1.85|
|[[:results:exp410|THZ531 0.11 to 0.125μM on day4 R07 exp410]]|1.88|
|[[:results:exp42|BI-6727 0.001μM R01 exp42]]|1.97|
|[[:results:exp51|Nifuroxazide 1μM R01 exp51]]|1.98|
|[[:results:exp347|Cyclosporin-A 0.8μM R07 exp347]]|1.99|
|[[:results:exp376|Losmapimod 1μM R07 exp376]]|2|
|[[:results:exp331|A-769662 20μM R07 exp331]]|2.06|
|[[:results:exp335|Aminopterin 0.005μM R07 exp335]]|2.12|
|[[:results:exp406|Thalidomide 20μM R07 exp406]]|2.14|
|[[:results:exp218|A-395 10μM R05 exp218]]|2.27|
|[[:results:exp357|Dorsomorphin 5μM R07 exp357]]|2.35|
|[[:results:exp46|HMS-I1 1μM R01 exp46]]|2.39|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:r:ruvbl2|RUVBL2]]|0.471|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 1853
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: N/A 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='NA Expression in NALM6 Cells: N/A'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>