NBPF1 [The Human Chemical-Genetic Interaction Map Project]

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======= NBPF1 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: NBPF1
  * **<color #00a2e8>Official Name</color>**: NBPF member 1
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=55672|55672]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q3BBV0|Q3BBV0]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=NBPF1&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20NBPF1|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/610501|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|DUF1220|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp527|Tanespimycin 14μM R08 exp527]]|-2.01|
|[[:results:exp8|Brefeldin A 0.02μM R00 exp8]]|-1.94|
|[[:results:exp19|Etoposide 1μM R00 exp19]]|-1.86|
|[[:results:exp25|Oligomycin-A 2μM R00 exp25]]|-1.83|
|[[:results:exp17|DABN 20μM R00 exp17]]|-1.73|
|[[:results:exp28|Pimelic-diphenylamide-106 5μM R00 exp28]]|-1.72|
|[[:results:exp306|Rapamycin 2μM R07 exp306]]|1.74|
|[[:results:exp310|2-Methoxyestradiol 0.55μM R07 exp310]]|1.91|
|[[:results:exp248|UM0131023 0.05μM R05 exp248]]|2.08|
|[[:results:exp326|CCT251545 20μM R07 exp326]]|2.35|
|[[:results:exp391|Pomalidomide 20μM R07 exp391]]|2.64|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:n:npipb5|NPIPB5]]|0.444|
|[[:human genes:t:tceb3cl2|TCEB3CL2]]|0.443|
|[[:human genes:f:fgf5|FGF5]]|0.436|
|[[:human genes:p:psmb4|PSMB4]]|0.423|
|[[:human genes:p:polr2j3|POLR2J3]]|0.418|
|[[:human genes:g:golga8k|GOLGA8K]]|0.409|
|[[:human genes:t:tceb3cl|TCEB3CL]]|0.408|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 2140
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 6.86 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='NBPF1 Expression in NALM6 Cells: 6.86'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>