OR5AR1 [The Human Chemical-Genetic Interaction Map Project]

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======= OR5AR1 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: OR5AR1
  * **<color #00a2e8>Official Name</color>**: olfactory receptor family 5 subfamily AR member 1 (gene/pseudogene)
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=219493|219493]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q8NGP9|Q8NGP9]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=OR5AR1&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20OR5AR1|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**:  Odorant receptor. {ECO:0000305}.

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|7tm 1|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|copper ion binding|
|odorant binding|
|olfactory receptor activity|
|detection of chemical stimulus involved in sensory perception of smell|
|sensory perception of smell|
|detection of chemical stimulus involved in sensory perception|
|detection of chemical stimulus|
|sensory perception of chemical stimulus|
|detection of stimulus involved in sensory perception|
|detection of stimulus|
|G protein-coupled receptor activity|
|sensory perception|
|G protein-coupled receptor signaling pathway|
|nervous system process|
|integral component of plasma membrane|
|system process|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp216|Erlotinib 10μM R05 exp216]]|-1.83|
|[[:results:exp393|Resminostat 0.5μM R07 exp393]]|-1.83|
|[[:results:exp521|Salinomycin 3.5μM R08 exp521]]|-1.79|
|[[:results:exp340|BN82002 4μM R07 exp340]]|-1.72|
|[[:results:exp482|Fas-L 44ng/ml R08 exp482]]|1.7|
|[[:results:exp270|Campthothecin 0.001μM R06 exp270]]|1.78|
|[[:results:exp153|SGC2096 2.6μM R03 exp153]]|2.22|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 15508
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: -7.68 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='OR5AR1 Expression in NALM6 Cells: -7.68'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>