PPAN-P2RY11 [The Human Chemical-Genetic Interaction Map Project]

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======= PPAN-P2RY11 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: N/A
  * **<color #00a2e8>Official Name</color>**: N/A
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: N/A
  * **<color #00a2e8>UniProt</color>**: N/A
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=PPAN-P2RY11&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20PPAN-P2RY11|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**:  May have a role in cell growth.

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|Brix|
|7tm 1|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|preribosome, large subunit precursor|
|ribosomal large subunit assembly|
|ribosome assembly|
|ribosomal large subunit biogenesis|
|ribonucleoprotein complex assembly|
|ribonucleoprotein complex subunit organization|
|ribosome biogenesis|
|ribonucleoprotein complex biogenesis|
|organelle assembly|
|cellular protein-containing complex assembly|
|protein-containing complex assembly|
|protein-containing complex subunit organization|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp34|Rotenone 20μM R00 exp34]]|-1.89|
|[[:results:exp2|5-Fluorouracil 20μM R00 exp2]]|-1.87|
|[[:results:exp259|6-Thio-2-deoxyguanosine 2μM R06 exp259]]|-1.77|
|[[:results:exp214|2-Deoxy-D-glucose 800μM R05 exp214]]|1.73|
|[[:results:exp272|CHIR-124 0.04μM R06 exp272]]|1.81|
|[[:results:exp391|Pomalidomide 20μM R07 exp391]]|2.09|
|[[:results:exp406|Thalidomide 20μM R07 exp406]]|2.23|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 726
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 4.61 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='PPAN-P2RY11 Expression in NALM6 Cells: 4.61'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>