RGPD6 [The Human Chemical-Genetic Interaction Map Project]

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======= RGPD6 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: RGPD6
  * **<color #00a2e8>Official Name</color>**: RANBP2 like and GRIP domain containing 6
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=729540|729540]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q99666|Q99666]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=RGPD6&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20RGPD6|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/612709|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|TPR 1|
|Ran BP1|
|GRIP|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='default' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
No hits were found.
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 396/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|1/1|
|909776.0|0/1|
|bile duct|17/28|
|blood|20/28|
|bone|13/26|
|breast|21/33|
|central nervous system|25/56|
|cervix|0/4|
|colorectal|9/17|
|esophagus|4/13|
|fibroblast|0/1|
|gastric|7/16|
|kidney|9/21|
|liver|11/20|
|lung|32/75|
|lymphocyte|13/16|
|ovary|13/26|
|pancreas|18/24|
|peripheral nervous system|7/16|
|plasma cell|11/15|
|prostate|1/1|
|skin|11/24|
|soft tissue|5/9|
|thyroid|1/2|
|upper aerodigestive|12/22|
|urinary tract|16/29|
|uterus|2/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 4420
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 4.18 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='RGPD6 Expression in NALM6 Cells: 4.18'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>