TCEB3C [The Human Chemical-Genetic Interaction Map Project]

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======= TCEB3C =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: ELOA3
  * **<color #00a2e8>Official Name</color>**: elongin A3
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=162699|162699]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/Q8NG57|Q8NG57]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=TCEB3C&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20TCEB3C|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**:  N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**:  The SIII (or elongin) transcription elongation factor complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. This complex is a heterotrimer, composed of the transcriptionally active subunit A, A2 or A3 (or elongin A, A2 or A3) and two regulatory subunits, B and C (or elongin B and C). This gene encodes subunit A3. A3 and A are ubiquitously expressed, whereas A2 is specifically expressed in the testis. [provided by RefSeq, Mar 2010]. 
  * **<color #00a2e8>UniProt Summary</color>**:  SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A3 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). {ECO:0000269|PubMed:11994304}.

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|Med26|
|Elongin A|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|elongin complex|
|transcription elongation from RNA polymerase II promoter|
|DNA-templated transcription, elongation|
|transcription by RNA polymerase II|
|transcription, DNA-templated|
|nucleic acid-templated transcription|
|RNA biosynthetic process|
|nucleobase-containing compound biosynthetic process|
|heterocycle biosynthetic process|
|aromatic compound biosynthetic process|
|organic cyclic compound biosynthetic process|
|cellular nitrogen compound biosynthetic process|
|RNA metabolic process|
|cellular macromolecule biosynthetic process|
|macromolecule biosynthetic process|
|gene expression|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp33|Rotenone 2μM R00 exp33]]|-1.97|
|[[:results:exp536|Vitamin-D3 40μM R08 exp536]]|-1.89|
|[[:results:exp469|CFI-400945 25μM R08 exp469]]|-1.86|
|[[:results:exp217|Mdivi-1 15μM R05 exp217]]|1.7|
|[[:results:exp232|Epothilone-D 0.004 to 0.006μM on day4 R05 exp232]]|1.74|
|[[:results:exp223|Cabazitaxel 0.001μM R05 exp223]]|1.75|
|[[:results:exp247|UM0130462 0.025 to 0.035μM day4 R05 exp247]]|1.75|
|[[:results:exp493|IL-3 9ng/ml R08 exp493]]|1.77|
|[[:results:exp464|Calcipotriol 5μM R08 exp464]]|1.81|
|[[:results:exp249|Vinorelbine 0.001μM R05 exp249]]|1.86|
|[[:results:exp53|Suberoylanilide-Hydroxamic-Acid 0.02μM R01 exp53]]|1.87|
|[[:results:exp362|GSK-J4 1μM R07 exp362]]|1.93|
|[[:results:exp218|A-395 10μM R05 exp218]]|1.94|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:p:psmb4|PSMB4]]|0.651|
|[[:human genes:t:ticrr|TICRR]]|0.624|
|[[:human genes:p:psmb2|PSMB2]]|0.618|
|[[:human genes:p:psma6|PSMA6]]|0.613|
|[[:human genes:r:rrp7a|RRP7A]]|0.612|
|[[:human genes:r:rps2|RPS2]]|0.605|
|[[:human genes:n:npipb5|NPIPB5]]|0.604|
|[[:human genes:t:tbc1d3h|TBC1D3H]]|0.601|
|[[:human genes:c:c1qtnf9b|C1QTNF9B]]|0.6|
|[[:human genes:c:chd4|CHD4]]|0.595|
|[[:human genes:o:orc1|ORC1]]|0.595|
|[[:human genes:t:tbc1d3g|TBC1D3G]]|0.59|
|[[:human genes:r:rpl35|RPL35]]|0.589|
|[[:human genes:t:tbc1d3f|TBC1D3F]]|0.588|
|[[:human genes:u:upf1|UPF1]]|0.586|
|[[:human genes:s:slc6a17|SLC6A17]]|0.584|
|[[:human genes:c:chaf1a|CHAF1A]]|0.581|
|[[:human genes:v:vasn|VASN]]|0.579|
|[[:human genes:c:ccna2|CCNA2]]|0.577|
|[[:human genes:g:golga6l1|GOLGA6L1]]|0.577|
|[[:human genes:p:polr2j3|POLR2J3]]|0.574|
|[[:human genes:c:cactin|CACTIN]]|0.572|
|[[:human genes:r:rps12|RPS12]]|0.571|
|[[:human genes:l:lrr1|LRR1]]|0.57|
|[[:human genes:d:ddtl|DDTL]]|0.568|
|[[:human genes:v:vps28|VPS28]]|0.566|
|[[:human genes:c:copg1|COPG1]]|0.564|
|[[:human genes:c:cdca3|CDCA3]]|0.56|
|[[:human genes:s:supt5h|SUPT5H]]|0.559|
|[[:human genes:a:aatf|AATF]]|0.559|
|[[:human genes:m:mt1e|MT1E]]|0.558|
|[[:human genes:p:psmd3|PSMD3]]|0.558|
|[[:human genes:s:slc4a1|SLC4A1]]|0.556|
|[[:human genes:o:orc6|ORC6]]|0.555|
|[[:human genes:t:tbc1d3|TBC1D3]]|0.554|
|[[:human genes:p:psmd14|PSMD14]]|0.553|
|[[:human genes:u:utp3|UTP3]]|0.551|
|[[:human genes:n:nup160|NUP160]]|0.551|
|[[:human genes:a:ankle2|ANKLE2]]|0.551|
|[[:human genes:t:tp53tg3b|TP53TG3B]]|0.55|
|[[:human genes:r:rad51|RAD51]]|0.55|
|[[:human genes:t:tbc1d3c|TBC1D3C]]|0.55|
|[[:human genes:g:golga6l3|GOLGA6L3]]|0.55|
|[[:human genes:t:tp53tg3|TP53TG3]]|0.549|
|[[:human genes:k:krt78|KRT78]]|0.548|
|[[:human genes:t:tp53tg3c|TP53TG3C]]|0.548|
|[[:human genes:d:dtl|DTL]]|0.548|
|[[:human genes:n:nupl1|NUPL1]]|0.547|
|[[:human genes:c:col2a1|COL2A1]]|0.547|
|[[:human genes:t:timeless|TIMELESS]]|0.547|
|[[:human genes:t:tbc1d3e|TBC1D3E]]|0.546|
|[[:human genes:t:tbc1d3k|TBC1D3K]]|0.546|
|[[:human genes:t:tbc1d3i|TBC1D3I]]|0.546|
|[[:human genes:t:tbc1d3l|TBC1D3L]]|0.546|
|[[:human genes:a:aamp|AAMP]]|0.545|
|[[:human genes:x:xylt2|XYLT2]]|0.545|
|[[:human genes:i:ik|IK]]|0.545|
|[[:human genes:w:wdr87|WDR87]]|0.544|
|[[:human genes:a:aqr|AQR]]|0.544|
|[[:human genes:c:cdc73|CDC73]]|0.542|
|[[:human genes:c:cbwd3|CBWD3]]|0.541|
|[[:human genes:t:tyms|TYMS]]|0.541|
|[[:human genes:c:c14orf93|C14orf93]]|0.54|
|[[:human genes:c:cdc6|CDC6]]|0.539|
|[[:human genes:p:psmc2|PSMC2]]|0.539|
|[[:human genes:g:golga6l4|GOLGA6L4]]|0.538|
|[[:human genes:p:pwp2|PWP2]]|0.538|
|[[:human genes:p:pole|POLE]]|0.537|
|[[:human genes:e:exosc9|EXOSC9]]|0.535|
|[[:human genes:s:supt6h|SUPT6H]]|0.535|
|[[:human genes:i:igfn1|IGFN1]]|0.534|
|[[:human genes:h:hivep3|HIVEP3]]|0.533|
|[[:human genes:r:rrn3|RRN3]]|0.532|
|[[:human genes:k:kctd17|KCTD17]]|0.532|
|[[:human genes:c:cbwd5|CBWD5]]|0.532|
|[[:human genes:p:psma7|PSMA7]]|0.532|
|[[:human genes:p:psmc1|PSMC1]]|0.53|
|[[:human genes:c:cope|COPE]]|0.527|
|[[:human genes:a:atp6v1c1|ATP6V1C1]]|0.526|
|[[:human genes:s:snrpa1|SNRPA1]]|0.525|
|[[:human genes:a:akirin2|AKIRIN2]]|0.525|
|[[:human genes:n:narfl|NARFL]]|0.524|
|[[:human genes:r:rpl6|RPL6]]|0.522|
|[[:human genes:n:npipb8|NPIPB8]]|0.522|
|[[:human genes:r:rpl30|RPL30]]|0.522|
|[[:human genes:a:atp6v1a|ATP6V1A]]|0.522|
|[[:human genes:t:tsg101|TSG101]]|0.52|
|[[:human genes:t:tfip11|TFIP11]]|0.52|
|[[:human genes:g:golga6a|GOLGA6A]]|0.52|
|[[:human genes:t:tspy8|TSPY8]]|0.519|
|[[:human genes:g:golga6l6|GOLGA6L6]]|0.517|
|[[:human genes:f:fam25b|FAM25B]]|0.517|
|[[:human genes:p:paf1|PAF1]]|0.516|
|[[:human genes:c:cln6|CLN6]]|0.516|
|[[:human genes:h:hap1|HAP1]]|0.516|
|[[:human genes:s:sf3a1|SF3A1]]|0.516|
|[[:human genes:p:pno1|PNO1]]|0.514|
|[[:human genes:g:golga8o|GOLGA8O]]|0.514|
|[[:human genes:b:bysl|BYSL]]|0.514|
|[[:human genes:p:psmb1|PSMB1]]|0.513|
|[[:human genes:z:znf830|ZNF830]]|0.512|
|[[:human genes:p:pigs|PIGS]]|0.512|
|[[:human genes:i:ints5|INTS5]]|0.512|
|[[:human genes:n:nol10|NOL10]]|0.512|
|[[:human genes:w:wdr75|WDR75]]|0.511|
|[[:human genes:p:psmc6|PSMC6]]|0.509|
|[[:human genes:n:nol12|NOL12]]|0.509|
|[[:human genes:t:twistnb|TWISTNB]]|0.508|
|[[:human genes:p:pola1|POLA1]]|0.507|
|[[:human genes:h:hist1h2be|HIST1H2BE]]|0.504|
|[[:human genes:i:iscu|ISCU]]|0.504|
|[[:human genes:a:atp6ap1|ATP6AP1]]|0.503|
|[[:human genes:f:fcn2|FCN2]]|0.503|
|[[:human genes:h:hist2h3c|HIST2H3C]]|0.503|
|[[:human genes:h:hist2h3a|HIST2H3A]]|0.503|
|[[:human genes:c:ctage4|CTAGE4]]|0.502|
|[[:human genes:m:mphosph10|MPHOSPH10]]|0.502|
|[[:human genes:a:atp6v1b2|ATP6V1B2]]|0.501|
|[[:human genes:n:napa|NAPA]]|0.501|
|[[:human genes:r:rps19bp1|RPS19BP1]]|0.501|
|[[:human genes:r:rnf113a|RNF113A]]|0.5|
|[[:human genes:n:nup153|NUP153]]|0.5|
|[[:human genes:c:ccdc116|CCDC116]]|0.5|
|[[:human genes:d:dock6|DOCK6]]|0.5|
|[[:human genes:p:pola2|POLA2]]|0.499|
|[[:human genes:c:cbwd6|CBWD6]]|0.499|
|[[:human genes:p:psmd11|PSMD11]]|0.499|
|[[:human genes:r:rbm39|RBM39]]|0.498|
|[[:human genes:f:fam231c|FAM231C]]|0.498|
|[[:human genes:c:ccdc94|CCDC94]]|0.498|
|[[:human genes:f:fam231a|FAM231A]]|0.498|
|[[:human genes:e:exd1|EXD1]]|0.497|
|[[:human genes:s:sf3a3|SF3A3]]|0.497|
|[[:human genes:p:pan2|PAN2]]|0.496|
|[[:human genes:d:ddt|DDT]]|0.495|
|[[:human genes:d:disp2|DISP2]]|0.495|
|[[:human genes:m:myb|MYB]]|0.495|
|[[:human genes:p:pcf11|PCF11]]|0.494|
|[[:human genes:s:scgb1c1|SCGB1C1]]|0.494|
|[[:human genes:c:copb1|COPB1]]|0.493|
|[[:human genes:p:psmc5|PSMC5]]|0.493|
|[[:human genes:e:eif4a3|EIF4A3]]|0.492|
|[[:human genes:p:polr2a|POLR2A]]|0.492|
|[[:human genes:d:dido1|DIDO1]]|0.491|
|[[:human genes:k:kpnb1|KPNB1]]|0.491|
|[[:human genes:r:rpl8|RPL8]]|0.489|
|[[:human genes:c:cdc45|CDC45]]|0.489|
|[[:human genes:m:myo1h|MYO1H]]|0.488|
|[[:human genes:a:acsf2|ACSF2]]|0.487|
|[[:human genes:p:polr2d|POLR2D]]|0.487|
|[[:human genes:r:rps9|RPS9]]|0.487|
|[[:human genes:p:psmd1|PSMD1]]|0.487|
|[[:human genes:r:rps5|RPS5]]|0.486|
|[[:human genes:s:slc38a7|SLC38A7]]|0.486|
|[[:human genes:p:pan3|PAN3]]|0.485|
|[[:human genes:r:rnpc3|RNPC3]]|0.485|
|[[:human genes:s:sh3bp1|SH3BP1]]|0.485|
|[[:human genes:p:plk1|PLK1]]|0.485|
|[[:human genes:p:phf2|PHF2]]|0.484|
|[[:human genes:a:atp6v0c|ATP6V0C]]|0.484|
|[[:human genes:c:cmya5|CMYA5]]|0.483|
|[[:human genes:t:taf1|TAF1]]|0.483|
|[[:human genes:e:exosc6|EXOSC6]]|0.481|
|[[:human genes:t:traip|TRAIP]]|0.48|
|[[:human genes:c:cdh24|CDH24]]|0.479|
|[[:human genes:c:cep192|CEP192]]|0.479|
|[[:human genes:t:tpx2|TPX2]]|0.479|
|[[:human genes:s:snip1|SNIP1]]|0.477|
|[[:human genes:r:rad21|RAD21]]|0.477|
|[[:human genes:s:sec13|SEC13]]|0.477|
|[[:human genes:r:rbbp5|RBBP5]]|0.477|
|[[:human genes:r:rps7|RPS7]]|0.477|
|[[:human genes:m:mcoln1|MCOLN1]]|0.477|
|[[:human genes:c:cwc22|CWC22]]|0.477|
|[[:human genes:u:utp20|UTP20]]|0.476|
|[[:human genes:p:ppfia4|PPFIA4]]|0.476|
|[[:human genes:p:psmd7|PSMD7]]|0.476|
|[[:human genes:r:rps19|RPS19]]|0.476|
|[[:human genes:m:madcam1|MADCAM1]]|0.476|
|[[:human genes:s:ssh2|SSH2]]|0.475|
|[[:human genes:t:terf2|TERF2]]|0.475|
|[[:human genes:a:adra1d|ADRA1D]]|0.474|
|[[:human genes:e:ebna1bp2|EBNA1BP2]]|0.474|
|[[:human genes:p:polr1a|POLR1A]]|0.473|
|[[:human genes:a:akt1s1|AKT1S1]]|0.473|
|[[:human genes:k:kiaa0947|KIAA0947]]|0.473|
|[[:human genes:n:nsf|NSF]]|0.472|
|[[:human genes:r:rrp9|RRP9]]|0.472|
|[[:human genes:k:kif3c|KIF3C]]|0.471|
|[[:human genes:c:clptm1|CLPTM1]]|0.47|
|[[:human genes:n:ncl|NCL]]|0.47|
|[[:human genes:r:rps3a|RPS3A]]|0.47|
|[[:human genes:r:rffl|RFFL]]|0.469|
|[[:human genes:d:dnm2|DNM2]]|0.469|
|[[:human genes:e:exosc5|EXOSC5]]|0.468|
|[[:human genes:m:mfsd12|MFSD12]]|0.468|
|[[:human genes:c:copa|COPA]]|0.468|
|[[:human genes:n:nup205|NUP205]]|0.468|
|[[:human genes:c:cgb2|CGB2]]|0.467|
|[[:human genes:d:dhx38|DHX38]]|0.467|
|[[:human genes:e:egr2|EGR2]]|0.467|
|[[:human genes:f:fam160a1|FAM160A1]]|0.467|
|[[:human genes:c:ctr9|CTR9]]|0.467|
|[[:human genes:p:prpf19|PRPF19]]|0.466|
|[[:human genes:a:aldh1b1|ALDH1B1]]|0.465|
|[[:human genes:n:nfatc4|NFATC4]]|0.464|
|[[:human genes:n:nup54|NUP54]]|0.464|
|[[:human genes:t:tp53tg3d|TP53TG3D]]|0.463|
|[[:human genes:m:med17|MED17]]|0.463|
|[[:human genes:p:parp3|PARP3]]|0.463|
|[[:human genes:z:zfand5|ZFAND5]]|0.462|
|[[:human genes:m:myt1l|MYT1L]]|0.462|
|[[:human genes:s:strn|STRN]]|0.462|
|[[:human genes:h:hgc6.3|HGC6.3]]|0.462|
|[[:human genes:g:gprin2|GPRIN2]]|0.462|
|[[:human genes:w:wdr43|WDR43]]|0.461|
|[[:human genes:c:ccdc64b|CCDC64B]]|0.461|
|[[:human genes:p:plekha4|PLEKHA4]]|0.46|
|[[:human genes:c:c2orf27b|C2orf27B]]|0.46|
|[[:human genes:p:prim1|PRIM1]]|0.46|
|[[:human genes:a:atp13a1|ATP13A1]]|0.46|
|[[:human genes:s:sart1|SART1]]|0.459|
|[[:human genes:e:exosc3|EXOSC3]]|0.459|
|[[:human genes:c:c3orf17|C3orf17]]|0.458|
|[[:human genes:e:exosc8|EXOSC8]]|0.457|
|[[:human genes:p:ppm1d|PPM1D]]|0.457|
|[[:human genes:s:sema6b|SEMA6B]]|0.457|
|[[:human genes:h:hist1h4b|HIST1H4B]]|0.457|
|[[:human genes:s:smtn|SMTN]]|0.456|
|[[:human genes:m:mdm2|MDM2]]|0.456|
|[[:human genes:a:atp1a3|ATP1A3]]|0.456|
|[[:human genes:o:or10g3|OR10G3]]|0.456|
|[[:human genes:s:scaf1|SCAF1]]|0.455|
|[[:human genes:p:pla2g4f|PLA2G4F]]|0.455|
|[[:human genes:r:rrp15|RRP15]]|0.454|
|[[:human genes:s:s1pr4|S1PR4]]|0.454|
|[[:human genes:p:psmb3|PSMB3]]|0.454|
|[[:human genes:a:arhgef35|ARHGEF35]]|0.453|
|[[:human genes:a:arcn1|ARCN1]]|0.453|
|[[:human genes:n:nufip2|NUFIP2]]|0.453|
|[[:human genes:r:ranbp2|RANBP2]]|0.453|
|[[:human genes:g:gid4|GID4]]|0.452|
|[[:human genes:a:ankle1|ANKLE1]]|0.452|
|[[:human genes:r:rps10|RPS10]]|0.451|
|[[:human genes:n:numa1|NUMA1]]|0.451|
|[[:human genes:n:naaladl1|NAALADL1]]|0.451|
|[[:human genes:o:ogfr|OGFR]]|0.45|
|[[:human genes:c:cox7a2l|COX7A2L]]|0.45|
|[[:human genes:c:clasp1|CLASP1]]|0.448|
|[[:human genes:d:ddx47|DDX47]]|0.447|
|[[:human genes:r:rpl34|RPL34]]|0.447|
|[[:human genes:i:ints6|INTS6]]|0.447|
|[[:human genes:s:syt9|SYT9]]|0.446|
|[[:human genes:c:cacna1a|CACNA1A]]|0.446|
|[[:human genes:c:copb2|COPB2]]|0.445|
|[[:human genes:b:brd2|BRD2]]|0.445|
|[[:human genes:m:med29|MED29]]|0.445|
|[[:human genes:t:tspy1|TSPY1]]|0.444|
|[[:human genes:p:psmd6|PSMD6]]|0.444|
|[[:human genes:s:sap30bp|SAP30BP]]|0.444|
|[[:human genes:l:lad1|LAD1]]|0.444|
|[[:human genes:c:crnkl1|CRNKL1]]|0.443|
|[[:human genes:d:dnttip2|DNTTIP2]]|0.443|
|[[:human genes:m:mylk3|MYLK3]]|0.441|
|[[:human genes:c:cnot1|CNOT1]]|0.441|
|[[:human genes:s:sult1a3|SULT1A3]]|0.441|
|[[:human genes:s:sult1a4|SULT1A4]]|0.441|
|[[:human genes:l:loc643669|LOC643669]]|0.44|
|[[:human genes:n:nbpf10|NBPF10]]|0.44|
|[[:human genes:m:med14|MED14]]|0.44|
|[[:human genes:h:hinfp|HINFP]]|0.44|
|[[:human genes:z:znf574|ZNF574]]|0.439|
|[[:human genes:s:sprr2b|SPRR2B]]|0.439|
|[[:human genes:x:xab2|XAB2]]|0.439|
|[[:human genes:m:mfrp|MFRP]]|0.438|
|[[:human genes:p:psmd2|PSMD2]]|0.438|
|[[:human genes:t:tuba8|TUBA8]]|0.438|
|[[:human genes:m:mat2a|MAT2A]]|0.437|
|[[:human genes:r:rilpl1|RILPL1]]|0.436|
|[[:human genes:d:ddx56|DDX56]]|0.436|
|[[:human genes:i:itga2b|ITGA2B]]|0.436|
|[[:human genes:r:rrp12|RRP12]]|0.436|
|[[:human genes:g:golga6b|GOLGA6B]]|0.435|
|[[:human genes:c:copz1|COPZ1]]|0.435|
|[[:human genes:g:gon4l|GON4L]]|0.434|
|[[:human genes:t:ttc31|TTC31]]|0.434|
|[[:human genes:n:nop16|NOP16]]|0.434|
|[[:human genes:m:msh5|MSH5]]|0.433|
|[[:human genes:r:rpl37a|RPL37A]]|0.433|
|[[:human genes:h:hnrnpa1|HNRNPA1]]|0.433|
|[[:human genes:p:pold1|POLD1]]|0.433|
|[[:human genes:t:top1mt|TOP1MT]]|0.433|
|[[:human genes:h:hnrnpc|HNRNPC]]|0.433|
|[[:human genes:n:nfya|NFYA]]|0.433|
|[[:human genes:z:znf655|ZNF655]]|0.432|
|[[:human genes:s:smg7|SMG7]]|0.432|
|[[:human genes:r:rps20|RPS20]]|0.432|
|[[:human genes:r:rpl9|RPL9]]|0.432|
|[[:human genes:r:rfpl3|RFPL3]]|0.431|
|[[:human genes:f:fbxw9|FBXW9]]|0.431|
|[[:human genes:a:atp6ap2|ATP6AP2]]|0.431|
|[[:human genes:p:polr2f|POLR2F]]|0.431|
|[[:human genes:f:fam20a|FAM20A]]|0.43|
|[[:human genes:i:isy1|ISY1]]|0.43|
|[[:human genes:n:nup62|NUP62]]|0.43|
|[[:human genes:a:atp6v0b|ATP6V0B]]|0.43|
|[[:human genes:s:srgap2c|SRGAP2C]]|0.429|
|[[:human genes:p:psmd8|PSMD8]]|0.429|
|[[:human genes:r:rplp1|RPLP1]]|0.428|
|[[:human genes:o:osbp|OSBP]]|0.428|
|[[:human genes:n:nol9|NOL9]]|0.428|
|[[:human genes:a:abhd8|ABHD8]]|0.428|
|[[:human genes:r:riok2|RIOK2]]|0.427|
|[[:human genes:r:ruvbl2|RUVBL2]]|0.427|
|[[:human genes:s:sfpq|SFPQ]]|0.427|
|[[:human genes:r:rpsa|RPSA]]|0.426|
|[[:human genes:s:smg1|SMG1]]|0.426|
|[[:human genes:p:psmc4|PSMC4]]|0.425|
|[[:human genes:r:rfc1|RFC1]]|0.424|
|[[:human genes:a:ahctf1|AHCTF1]]|0.424|
|[[:human genes:z:znf106|ZNF106]]|0.424|
|[[:human genes:t:tgm5|TGM5]]|0.424|
|[[:human genes:r:rps28|RPS28]]|0.423|
|[[:human genes:s:snrnp70|SNRNP70]]|0.422|
|[[:human genes:c:chchd3|CHCHD3]]|0.422|
|[[:human genes:n:nup98|NUP98]]|0.422|
|[[:human genes:a:abt1|ABT1]]|0.422|
|[[:human genes:n:nup85|NUP85]]|0.421|
|[[:human genes:r:rps3|RPS3]]|0.421|
|[[:human genes:c:ctage9|CTAGE9]]|0.421|
|[[:human genes:c:c2orf27a|C2orf27A]]|0.421|
|[[:human genes:n:nup43|NUP43]]|0.42|
|[[:human genes:m:mdn1|MDN1]]|0.42|
|[[:human genes:m:mms22l|MMS22L]]|0.42|
|[[:human genes:a:atxn1|ATXN1]]|0.42|
|[[:human genes:m:mtch2|MTCH2]]|0.42|
|[[:human genes:s:sf3b2|SF3B2]]|0.419|
|[[:human genes:n:ncapg|NCAPG]]|0.419|
|[[:human genes:r:rrp1|RRP1]]|0.419|
|[[:human genes:g:gar1|GAR1]]|0.419|
|[[:human genes:e:eif3g|EIF3G]]|0.418|
|[[:human genes:z:znf219|ZNF219]]|0.417|
|[[:human genes:s:sult2b1|SULT2B1]]|0.417|
|[[:human genes:c:ckap5|CKAP5]]|0.417|
|[[:human genes:a:acbd4|ACBD4]]|0.416|
|[[:human genes:r:rangap1|RANGAP1]]|0.416|
|[[:human genes:m:myo18a|MYO18A]]|0.416|
|[[:human genes:t:ttyh1|TTYH1]]|0.416|
|[[:human genes:c:casc3|CASC3]]|0.416|
|[[:human genes:s:shpk|SHPK]]|0.416|
|[[:human genes:c:csnk1a1|CSNK1A1]]|0.416|
|[[:human genes:n:nol8|NOL8]]|0.415|
|[[:human genes:u:ubl5|UBL5]]|0.415|
|[[:human genes:p:psap|PSAP]]|0.415|
|[[:human genes:n:nipbl|NIPBL]]|0.415|
|[[:human genes:m:mbtd1|MBTD1]]|0.414|
|[[:human genes:d:dhfr|DHFR]]|0.413|
|[[:human genes:c:cebpz|CEBPZ]]|0.413|
|[[:human genes:r:rpl10a|RPL10A]]|0.411|
|[[:human genes:n:ngdn|NGDN]]|0.411|
|[[:human genes:t:trim52|TRIM52]]|0.41|
|[[:human genes:p:polr2h|POLR2H]]|0.41|
|[[:human genes:f:fam86b2|FAM86B2]]|0.409|
|[[:human genes:p:pde4dip|PDE4DIP]]|0.409|
|[[:human genes:p:pole2|POLE2]]|0.409|
|[[:human genes:t:trappc11|TRAPPC11]]|0.409|
|[[:human genes:p:pdcd11|PDCD11]]|0.409|
|[[:human genes:c:cdt1|CDT1]]|0.408|
|[[:human genes:r:rps11|RPS11]]|0.408|
|[[:human genes:s:sel1l|SEL1L]]|0.408|
|[[:human genes:t:tinf2|TINF2]]|0.408|
|[[:human genes:v:vps54|VPS54]]|0.407|
|[[:human genes:u:uqcrh|UQCRH]]|0.406|
|[[:human genes:s:setd1a|SETD1A]]|0.405|
|[[:human genes:p:pdcd7|PDCD7]]|0.405|
|[[:human genes:n:nuf2|NUF2]]|0.405|
|[[:human genes:u:ube2q2l|UBE2Q2L]]|0.405|
|[[:human genes:d:dand5|DAND5]]|0.405|
|[[:human genes:d:diexf|DIEXF]]|0.405|
|[[:human genes:c:chmp4b|CHMP4B]]|0.404|
|[[:human genes:r:rilpl2|RILPL2]]|0.404|
|[[:human genes:h:hist2h2bf|HIST2H2BF]]|0.403|
|[[:human genes:b:bid|BID]]|0.403|
|[[:human genes:t:tgfbrap1|TGFBRAP1]]|0.402|
|[[:human genes:n:nup214|NUP214]]|0.402|
|[[:human genes:r:rrm2|RRM2]]|0.402|
|[[:human genes:s:stil|STIL]]|0.402|
|[[:human genes:f:fbl|FBL]]|0.402|
|[[:human genes:p:prpf3|PRPF3]]|0.401|
|[[:human genes:t:terf1|TERF1]]|0.4|
|[[:human genes:p:plrg1|PLRG1]]|0.4|
|[[:human genes:h:hk1|HK1]]|0.4|
|[[:human genes:t:tspy2|TSPY2]]|0.4|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 558
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: -4.01 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='TCEB3C Expression in NALM6 Cells: -4.01'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>