TMEM110-MUSTN1 [The Human Chemical-Genetic Interaction Map Project]

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======= TMEM110-MUSTN1 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: N/A
  * **<color #00a2e8>Official Name</color>**: N/A
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: N/A
  * **<color #00a2e8>UniProt</color>**: N/A
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=TMEM110-MUSTN1&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20TMEM110-MUSTN1|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: N/A

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='primary' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|DUF3661|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
|activation of store-operated calcium channel activity|
|positive regulation of store-operated calcium channel activity|
|cortical endoplasmic reticulum|
|regulation of store-operated calcium channel activity|
|calcium-mediated signaling using intracellular calcium source|
|calcium channel regulator activity|
|positive regulation of calcium ion transmembrane transporter activity|
|positive regulation of cation channel activity|
|positive regulation of calcium ion transmembrane transport|
|regulation of calcium ion transmembrane transporter activity|
|positive regulation of ion transmembrane transporter activity|
|positive regulation of transporter activity|
|positive regulation of calcium ion transport|
|positive regulation of cation transmembrane transport|
|calcium-mediated signaling|
|regulation of calcium ion transmembrane transport|
|positive regulation of ion transmembrane transport|
|regulation of cation channel activity|
|positive regulation of transmembrane transport|
|regulation of calcium ion transport|
|regulation of ion transmembrane transporter activity|
|regulation of transmembrane transporter activity|
|positive regulation of ion transport|
|regulation of transporter activity|
|regulation of cation transmembrane transport|
|second-messenger-mediated signaling|
|regulation of metal ion transport|
|regulation of ion transmembrane transport|
|regulation of transmembrane transport|
|regulation of ion transport|
|positive regulation of transport|
|intracellular signal transduction|
|positive regulation of molecular function|
|regulation of transport|
|membrane|
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='default' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp496|Lead acetate 990μM R08 exp496]]|-1.82|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
No correlation found to any other genes in chemogenomics.
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: N/A
^Tissue^Fraction Of Cell Lines Where Essential^
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 8427
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 4.3 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='TMEM110-MUSTN1 Expression in NALM6 Cells: 4.3'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>