TRAPPC13 [The Human Chemical-Genetic Interaction Map Project]

This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong.
======= TRAPPC13 =======


== Gene Information ==
  * **<color #00a2e8>Official Symbol</color>**: TRAPPC13
  * **<color #00a2e8>Official Name</color>**: trafficking protein particle complex 13
  * **<color #00a2e8>Aliases and Previous Symbols</color>**: N/A
  * **<color #00a2e8>Entrez ID</color>**: [[https://www.ncbi.nlm.nih.gov/gene/?term=80006|80006]]
  * **<color #00a2e8>UniProt</color>**: [[https://www.uniprot.org/uniprot/A5PLN9|A5PLN9]]
  * **<color #00a2e8>Interactions</color>**: [[https://thebiogrid.org/search.php?search=TRAPPC13&organism=9606|BioGRID]]
  * **<color #00a2e8>PubMed articles</color>**: [[https://www.ncbi.nlm.nih.gov/pubmed/?term=gene%20TRAPPC13|Open PubMed]]
  * **<color #00a2e8>OMIM</color>**: [[https://omim.org/entry/621423|Open OMIM]]

== Function Summary ==
  * **<color #00a2e8>Entrez Summary</color>**: N/A
  * **<color #00a2e8>UniProt Summary</color>**: N/A

<button type='primary' size='sm' modal='Pfam_Domains'>Pfam Domains</button>
<button type='default' size='sm' modal='GO_terms'>GO Terms</button>


<modal id='Pfam_Domains' size='lg' title='Pfam Domains'>
|DUF974|
</modal>

<modal id='GO_terms' size='lg' title='GO Terms'>
No GO term information is available for this gene.
</modal>
\\

 === CRISPR Data ===
<button type='primary' size='small' modal='Compound_Hit'>Compound Hit</button>
<button type='primary' size='small' modal='Most_Correlated_Genes'>Most Correlated Genes in Chemogenomics</button>
<button type='primary' size='small' modal='Essential_Avana'>Tissues where Essential in the Avana Dataset (DepMap 20Q1)</button>

<modal id='Compound_Hit' size='lg' title='Compound Hit'>
^Screen^Score^
|[[:results:exp445|∆-9-Tetrahydrocannabinol 30μM R08 exp445]]|-3.09|
|[[:results:exp466|Cannabidiol 20μM R08 exp466]]|-2.7|
|[[:results:exp79|Q15 2.7μM R02 exp79]]|-2.39|
|[[:results:exp539|42°C R08 exp539]]|-2.25|
|[[:results:exp434|Vemurafenib 6.6μM R08 exp434]]|-2.19|
|[[:results:exp100|NFN1 1μM R03 exp100]]|-2.12|
|[[:results:exp454|Bafilomycin-A1 0.009μM R08 exp454]]|-2.08|
|[[:results:exp507|Monensin 0.3μM R08 exp507]]|-2.08|
|[[:results:exp515|PU-H71 1μM R08 exp515]]|-2.05|
|[[:results:exp282|Fluvastatin 2.2μM R06 exp282]]|-1.87|
|[[:results:exp17|DABN 20μM R00 exp17]]|-1.86|
|[[:results:exp27|Pimelic-diphenylamide-106 0.5μM R00 exp27]]|1.72|
|[[:results:exp35|TRAIL 5ng/ml R00 exp35]]|1.84|
|[[:results:exp28|Pimelic-diphenylamide-106 5μM R00 exp28]]|1.86|
|[[:results:exp1|5-Fluorouracil 2μM R00 exp1]]|1.87|
|[[:results:exp36|TRAIL 50ng/ml R00 exp36]]|3.31|
</modal>

<modal id='Most_Correlated_Genes' size='lg' title='Most Correlated Genes in Chemogenomics'>
^Gene^Correlation^
|[[:human genes:c:cog7|COG7]]|0.407|
</modal>

<modal id='Essential_Avana' size='lg' title='Tissues where Essential in the Avana Dataset (DepMap 20Q1)'>
Global Fraction of Cell Lines Where Essential: 1/739
^Tissue^Fraction Of Cell Lines Where Essential^
|1290807.0|0/1|
|909776.0|0/1|
|bile duct|0/28|
|blood|0/28|
|bone|0/26|
|breast|0/33|
|central nervous system|0/56|
|cervix|0/4|
|colorectal|0/17|
|esophagus|0/13|
|fibroblast|0/1|
|gastric|0/16|
|kidney|0/21|
|liver|0/20|
|lung|0/75|
|lymphocyte|0/16|
|ovary|0/26|
|pancreas|0/24|
|peripheral nervous system|0/16|
|plasma cell|0/15|
|prostate|0/1|
|skin|0/24|
|soft tissue|0/9|
|thyroid|0/2|
|upper aerodigestive|0/22|
|urinary tract|0/29|
|uterus|0/5|
</modal>

== Essentiality in NALM6  ==
    * **<color #00a2e8>Essentiality Rank</color>**: 13810
    * **<color #00a2e8>Expression level (log2 read counts)</color>**: 5.4 
<button type='primary' size='small' modal='Dist_expr'>Expression Distribution</button>
<modal id='Dist_expr' size='lg' title='TRAPPC13 Expression in NALM6 Cells: 5.4'>
{{:chemogenomics:nalm6 dist.png?nolink |}}
</modal>